16867-28-0

Basic information

• Product Name: 2,6-Dimethyl-4H-pyrido[1,2-a]pyrimidin-4-one
• Synonyms: 2,6-Dimethyl-4H-pyrido[1,2-a]pyrimidin-4-one
• CAS NO: 16867-28-0
• Molecular Formula: C10H10N2O
• Molecular Weight: 174.2
• Mol File: 16867-28-0.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,6-Dimethyl-4H-pyrido[1,2-a]pyrimidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dimethyl-4H-pyrido[1,2-a]pyrimidin-4-one(16867-28-0)
• EPA Substance Registry System: 2,6-Dimethyl-4H-pyrido[1,2-a]pyrimidin-4-one(16867-28-0)

Safety Data

• Hazardous Substances Data: 16867-28-0(Hazardous Substances Data)

Usage

Chemical compound

2,6-Dimethyl-4H-pyrido[1,2-a]pyrimidin-4-one

Class

Pyrido[1,2-a]pyrimidin-4-one

Heterocyclic compound

A compound with a pyrimidine ring fused to a pyridine ring

Methyl groups

Two methyl groups attached at the 2 and 6 positions of the pyridine ring

Usage

Commonly used in the pharmaceutical industry as a building block for the synthesis of various bioactive compounds

Applications

Valuable intermediate in the production of pharmaceuticals, agrochemicals, and other fine chemicals

Potential applications

Medicinal chemistry and drug discovery due to its diverse biological activities

Upstream product

• 1824-81-3 2-Amino-6-methylpyridine 
• 105-45-3 acetoacetic acid methyl ester 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 65896-28-8 1,8-naphthyridine-2,7-dicarboxaldehyde 
• 14903-78-7 2,7-dimethyl-[1,8]naphthyridine 

Relevant articles and documents

Practical Synthesis of 1,8-Naphthyridine-2,7-dialdehydes Syntone

Several synthetic approaches for synthesizing 1,8-naphthyridines were tested. Reliable protocols for synthesis of some new 1,8-naphthyridine-2,7-dialdehydes were developed starting from 2-amino-6-methylpyridine and acetoacetate. The dialdehyde were found

Solvent-free synthesis of 4H-Pyrido[1,2-a]pyrimidin-4-ones catalyzed by BiCl3: A green route to a privileged backbone

An extensive array of 4H-pyrido[1,2-a]pyrimidin-4-ones have been synthesized from commercially available 2-aminopyridines and β-oxo esters with excellent yields under solvent-free conditions. The reaction, catalyzed by cheap and nontoxic BiCl3,

Synthesis and antileishmanial activity of some pyridopyrimidines and phenanthrolines

Synthesis and in vitro biological evaluation for antileishmanial activity of a series of pyridopyrimidines, phenanthrolines are reported.Amongst pyridopyrimidines, compounds 6,7 and 9 have been found to possess promising activity.However, all the tested phenanthroline derivatives exhibit moderate to good anti-leishmania activity.