16874-02-5

Basic information

• Product Name: L-Valine, N-[(phenylmethoxy)carbonyl]-, 1,1-dimethylethyl ester
• CAS NO: 16874-02-5
• Molecular Formula: C17H25NO4
• Molecular Weight: 307.39
• Mol File: 16874-02-5.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: L-Valine, N-[(phenylmethoxy)carbonyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Valine, N-[(phenylmethoxy)carbonyl]-, 1,1-dimethylethyl ester(16874-02-5)
• EPA Substance Registry System: L-Valine, N-[(phenylmethoxy)carbonyl]-, 1,1-dimethylethyl ester(16874-02-5)

Safety Data

• Hazardous Substances Data: 16874-02-5(Hazardous Substances Data)

Upstream product

• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 115-11-7 isobutene 
• 507-19-7 t-butyl bromide 
• 75-65-0 tert-butyl alcohol 
• 501-53-1 benzyl chloroformate 
• 72-18-4 L-valine 
• 13211-31-9 tert-butyl L-valinate 
• 13734-41-3 t-Boc-L-valine 

Downstream Products

• 79113-77-2 Z-Ala-Val-Gly-OBu^t 
• 1448616-20-3 benzyl ((S)-1-(((S)-1-(benzo[d]thiazol-2-yl)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate 
• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 1353757-55-7 (S,E)-tert-butyl 2-isopropyl-2-(pyrrolidin-1-yl)-4-(p-toluenesulfonyl)but-3-enoate 
• 53159-55-0 (S)-tert-butyl 2-((S)-2-(((benzyloxy)carbonyl)amino)propanamido)-3-methylbutanoate 
• 13211-31-9 tert-butyl L-valinate 
• 97277-24-2 Boc-Tyr-Arg(NO₂)-Lys(Z)-Asp(OBzl)-Val-OBu^t 
• 100103-14-8 Boc-Tyr-Arg(NO₂)-D-Lys(Z)-Asp(OBzl)-Val-OBu^t 
• 96356-59-1 cyclo<-Tyr-Arg-D-Lys-Asp-Val->*2AcOH 
• 100164-91-8 cyclo<-Tyr-Arg-D-Lys-Asp-D-Val->*2AcOH 
• 100017-96-7 cyclo<-Tyr-Arg(NO2)-D-Lys(Z)-Asp(OBzl)-D-Val-> 
• 97251-02-0 Ddz-Asp(OBzl)-Val-OBu^t 
• 97251-05-3 H-Asp(OBzl)-Val-OBu^t*TFA 
• 97268-33-2 H-Val-OBu^t*TosOH 

Relevant articles and documents

Scavenging of fluorinated N,N′-dialkylureas by hydrogen binding: A novel separation method for fluorous synthesis

(matrix presented) A dramatic solubility increase in fluorous solvents is observed for N,N′-di(polyfluoroalkyl)ureas when hydrogen binding complexes are formed with commercially available perfluoroalkanoic acid scavengers. As a case example, analytically pure peptides and esters are obtained using this novel separation method.

Chiral tetraaryl-and tetraalkynylborates as chiral solvating agents for tetraalkylammonium salts

The application of tetracarbon-substituted chiral borate sodium salts (NaBR*4) as NMR chiral solvating agents for various tetraalkylammonium salts (R4NX) has been successfully demonstrated. Ion exchange between R4NX and NaBR*4 proceeded in excellent yields and provided the corresponding dia-stereomeric salts (R4NBR*4). The ee values of the R4NX salts were determined by1H NMR analysis of R4NBR*4. Two types of chiral borates, tetraaryl-and tetraalkynylborates with optically active 1,1′-binaphthyl components were used. At the beginning of this research, we investigated the efficacy of a known chiral tetraar-ylborate developed by Pommerening et al. for R4NX. To expand the possibility of further structural design of the chiral borate, we designed chiral tetraalkynylborates as a new structure. Their synthesis and application are also described.

Asymmetric α-2-tosylethenylation of N,N-dialkyl-l-amino acid esters via the formation of non-racemic ammonium enolates

Asymmetric α-2-tosylethenylation of (S)-2-(pyrrolidin-1-yl)propanoic acid esters was shown to produce good yields with high enantioselectivities. The reaction proceeds via the formation of a non-racemic ammonium enolate without an external source of chirality.