16874-08-1

Basic information

• Product Name: L-ISOLEUCINE-TERT-BUTYL ESTER DIBENZENE&
• Synonyms: L-ISOLEUCINE-TERT-BUTYL ESTER DIBENZENE&;tert-butyl L-isoleucinate;L-Isoleucine tert-butyl ester dibenzenesulfonimide salt;Isoleucine tert-butyl ester;L-Isoleucine 1,1-dimethylethyl ester;Einecs 240-901-8;DRWKBZREIMLHDX-YUMQZZPRSA-N
• CAS NO: 16874-08-1
• Molecular Formula: C₁₀H₂₁NO₂
• Molecular Weight: 187.27924
• EINECS: 240-901-8
• Mol File: 16874-08-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 134-135 °C
• Boiling Point: 222.4°Cat760mmHg
• Flash Point: 90.3°C
• Appearance: /
• Density: 0.929g/cm³
• Vapor Pressure: 0.102mmHg at 25°C
• Refractive Index: 1.444
• PKA: 7.94±0.39(Predicted)
• CAS DataBase Reference: L-ISOLEUCINE-TERT-BUTYL ESTER DIBENZENE&(CAS DataBase Reference)
• NIST Chemistry Reference: L-ISOLEUCINE-TERT-BUTYL ESTER DIBENZENE&(16874-08-1)
• EPA Substance Registry System: L-ISOLEUCINE-TERT-BUTYL ESTER DIBENZENE&(16874-08-1)

Safety Data

• Hazardous Substances Data: 16874-08-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H21NO2/c1-6-7(2)8(11)9(12)13-10(3,4)5/h7-8H,6,11H2,1-5H3

Upstream product

• 73-32-5 L-isoleucine 
• 115-11-7 isobutene 
• 3160-59-6 N-Cbz-L-Isoleucine 
• 540-88-5 acetic acid tert-butyl ester 
• 73-32-5 L-isoleucine 
• 319-78-8 isoleucine 
• 69320-89-4 L-isoleucine tert-butyl ester hydrochloride 
• 16881-43-9 1,1-dimethylethyl N-[(phenylmethyl)carbonyl]-L-isoleucinate 

Downstream Products

• 1147136-26-2 C₂₁H₃₂N₂O₆ 
• 1262052-82-3 tert-butyl (2S,3S)-2-(8-(benzyloxy)-1,5-dihydroxy-3-methyl-7,12-dioxobenzo[b]phenanthridin-6(5H,7H,12H)-yl)-3-methylpentanoate 
• 1316848-11-9 (S)-benzyl 3-((S)-3-(tert-butoxy)-2-((S)-sec-butyl)-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)pyrrolidine-1-carboxylate 
• 1316848-25-5 (S)-1-((S)-1-((R)-2-((R)-1-(benzyloxy)ethyl)-5-oxo-2,5-dihydro-1H-pyrrol-3-yl)pyrrolidin-3-yl)-4-(tert-butoxy)-5-((S)-sec-butyl)-1H-pyrrol-2(5H)-one 
• 1316848-26-6 benzyl 2-((S)-3-((S)-3-((S)-3-(tert-butoxy)-2-((S)-sec-butyl)-5-oxo-2,5-dihydro-1H-pyrrol-1-yl)pyrrolidin-1-yl)-5-oxo-2,5-dihydro-1H-pyrrol-2-yl)acetate 
• 856865-83-3 N-α-methyl-N-α-(o-nitrobenzenesulfonyl)-L-isoleucine 
• 84569-78-8 leucyl>isoleucin-tert-butylester-chlorid 

Relevant articles and documents

Overcoming the Deallylation Problem: Palladium(II)-Catalyzed Chemo-, Regio-, and Stereoselective Allylic Oxidation of Aryl Allyl Ether, Amine, and Amino Acids

We report herein a Pd(II)/bis-sulfoxide-catalyzed intramolecular allylic C-H acetoxylation of aryl allyl ether, amine, and amino acids with the retention of a labile allyl moiety. Mechanistically, the reaction proceeds through a distinct double-bond isomerization from the allylic to the vinylic position followed by intramolecular carboxypalladation and the β-hydride elimination pathway. For the first time, C-H oxidation of N-allyl-protected amino acids to furnish five-membered heterocycles through 1,3-syn-addition is established with excellent diastereoselectivity.

HIV protease inhibiting compounds

A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.