Tert-butyl (2S,3S)-2-amino-3-methylpentanoate

Base Information Edit

Chemical Name:Tert-butyl (2S,3S)-2-amino-3-methylpentanoate
CAS No.:16874-08-1
Molecular Formula:C10H21 N O2
Molecular Weight:187.282
Hs Code.:2922499990
European Community (EC) Number:240-901-8
UNII:ME3Y22XVA7
Nikkaji Number:J236.878A
ChEMBL ID:CHEMBL1229069
Mol file:16874-08-1.mol

Synonyms:16874-08-1;TERT-BUTYL (2S,3S)-2-AMINO-3-METHYLPENTANOATE;tert-Butyl L-isoleucinate;L-Isoleucine-tert-Butyl ester dibenzene sulfimide salt;L-ISOLEUCINE t-BUTYL ESTER;ME3Y22XVA7;L-Isoleucine, 1,1-dimethylethyl ester;isoleucine t-butyl ester;isoleucine tert-butyl ester;l-isoleucine tert-butyl ester;(L)-isoleucine t-butyl ester;SCHEMBL919004;CHEMBL1229069;DRWKBZREIMLHDX-YUMQZZPRSA-N;L-isoleucine 1,1-dimethylethylester;AKOS010396103;EN300-149304;TERT-BUTYL(2S,3S)-2-AMINO-3-METHYLPENTANOATE

Suppliers and Price of Tert-butyl (2S,3S)-2-amino-3-methylpentanoate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Tert-butyl (2S,3S)-2-amino-3-methylpentanoate Edit

Chemical Property:

Vapor Pressure:0.102mmHg at 25°C
Melting Point:134-135 °C
Boiling Point:222.4°Cat760mmHg
PKA:7.94±0.39(Predicted)
Flash Point:90.3°C
PSA：52.32000
Density:0.929g/cm³
LogP:2.40180
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:187.157228913
Heavy Atom Count:13
Complexity:172

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(C)C(C(=O)OC(C)(C)C)N
Isomeric SMILES:CC[C@H](C)[C@@H](C(=O)OC(C)(C)C)N

Technology Process of Tert-butyl (2S,3S)-2-amino-3-methylpentanoate

There total 9 articles about Tert-butyl (2S,3S)-2-amino-3-methylpentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 16881-43-9
1,1-dimethylethyl N-[(phenylmethyl)carbonyl]-L-isoleucinate

: 16874-08-1
L-Isoleucin-tert-butylester

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/ja01498a032

Reference yield:

: 3160-59-6
N-Cbz-L-Isoleucine

: 16874-08-1
L-Isoleucin-tert-butylester

Guidance literature:: Multi-step reaction with 2 steps

1: H₂SO₄ / CH₂Cl₂

2: H₂ / Pd-C / ethanol

With sulfuric acid; hydrogen; palladium on activated charcoal; In ethanol; dichloromethane;
DOI:10.1021/ja01498a032