168772-32-5

Usage

Explanation

The compound consists of 14 carbon atoms, 21 hydrogen atoms, 1 nitrogen atom, and 4 oxygen atoms.

Explanation

The sum of the atomic weights of all the atoms in the molecule.

Explanation

The compound features a unique ring structure with an oxygen atom in one ring and a nitrogen atom in the other, connected at a common carbon atom.

Explanation

The compound contains a carboxyl functional group, which is a key feature in many biologically active molecules and can participate in various chemical reactions.

Explanation

The compound has a formyl group, which is an aldehyde functional group with potential applications in organic synthesis and materials science.

Explanation

The carboxylic acid group is esterified with a tert-butyl group (1,1-dimethylethyl), which can influence the compound's reactivity, stability, and solubility.

Explanation

The compound is chiral, meaning it has a central carbon atom (C3) bonded to four different groups. The (3S)configuration indicates the spatial arrangement of these groups.

Explanation

Due to its unique structure and functional groups, the compound may have various applications in these fields, such as drug development, catalysts, or advanced materials.

Molecular weight

267.32 g/mol

Spiro ring system

One oxa (oxygen-containing) and one aza (nitrogen-containing) rings connected in a spiro manner

Carboxylic acid group

Presence of a -COOH group

Formyl group

Presence of a -CHO group

1,1-Dimethylethyl ester

Esterification of the carboxylic acid group with a 1,1-dimethylethyl group

Chiral compound

Configuration of (3S)-

Potential applications

Pharmaceutical, organic synthesis, and materials science

Upstream product

• 171623-05-5 (3S)-3-hydroxymethyl-1-oxa-4-azaspiro<4,5>decane-4-carboxylic acid 4-tert-butyl ester 
• 171623-06-6 1-oxa-4-azaspiro<4,5>decane-(3R)-3,4-dicarboxylic acid 4-tert-butyl ester 3-methyl ester 
• 95715-85-8 2-(tert-butoxycarbonylamino)-3-hydroxypropionic acid methyl ester 

Downstream Products

• 182958-16-3 (3S)-3-((1S)-1-hydroxyphenylmethyl)-1-oxa-4-azaspiro[4,5]decane-4-carboxylic acid tert-butyl ester 
• 197778-01-1 3-[(4-benzyloxy-3-chloro-phenyl)-hydroxy-methyl]-1-oxa-4-aza-spiro[4.5]decane-4-carboxylic acid tert-butyl ester 
• 183075-33-4 tert-butyl (1,3-dihydroxy-1-phenylpropan-2-yl)carbamate 
• 168772-33-6 (S)-3-((R)-1-Benzoyloxy-3-ethoxycarbonyl-prop-2-ynyl)-1-oxa-4-aza-spiro[4.5]decane-4-carboxylic acid tert-butyl ester 
• 197777-86-9 (2S,3R)-3-acetoxy-3-(4-benzyloxy-3-chlorophenyl)-2-tert-butoxycarbonylamino-1,2-cyclohexylidenepropan-1-ol 
• 197777-97-2 (2S,3S)-3-acetoxy-3-(4-benzyloxy-3-chlorophenyl)-2-tert-butoxycarbonylamino-1,2-cyclohexylidenepropan-1-ol 
• 197777-96-1 ((1R,2R)-2-(tert-Butyl-dimethyl-silanyloxy)-2-(3-chloro-4-hydroxy-phenyl)-1-{(S)-2-cyano-1-[(R)-1-(3-fluoro-4-nitro-phenyl)-2-methoxy-ethylcarbamoyl]-ethylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester 
• 197778-04-4 (2R,3R)-3-(4-Benzyloxy-3-chloro-phenyl)-2-tert-butoxycarbonylamino-3-(tert-butyl-dimethyl-silanyloxy)-propionic acid 
• 197778-03-3 (2R,3R)-3-Acetoxy-3-(4-benzyloxy-3-chloro-phenyl)-2-tert-butoxycarbonylamino-propionic acid 
• 197778-02-2 (2S,3R)-3-acetoxy-3-(4-benzyloxy-3-chlorophenyl)-2-tert-butoxycarbonylaminopropan-1-ol 
• 197777-87-0 (2R,3R)-3-(4-benzyloxy-3-chlorophenyl)-2-tert-butoxycarbonylamino-3-hydroxypropionic acid 
• 197777-88-1 (2R,3R)-2-tert-Butoxycarbonylamino-3-(tert-butyl-dimethyl-silanyloxy)-3-(3-chloro-4-hydroxy-phenyl)-propionic acid 

Relevant academic research and scientific papers

Grignard reactions to chiral oxazolidine aldehydes

Modest to high levels of asymmetric induction are observed with Grignard additions to Garner type aldehydes. The resultant secondary alcohols are important precursors of chiral building blocks for asymmetric synthesis and we have demonstrated that they can be readily converted into their respective γ-hydroxy-β-amino alcohols and β-hydroxyamino acids. Additionally, aryloxy ethers, important components of many natural products, can be obtained from these precursors.