197777-86-9

Upstream product

• 108-24-7 acetic anhydride 
• 168772-32-5 (S)-Garner's aldehyde 
• 197777-97-2 (2S,3S)-3-acetoxy-3-(4-benzyloxy-3-chlorophenyl)-2-tert-butoxycarbonylamino-1,2-cyclohexylidenepropan-1-ol 
• 220214-81-3 (2S)-3-(4-benzyloxy-3-chlorophenyl)-2-tert-butoxycarbonylamino-1,2-cyclohexylidene-3-oxopropan-1-ol 
• 95-57-8 2-monochlorophenol 
• 3964-56-5 4-bromo-2-chlorophenol 
• 56872-27-6 1-(benzyloxy)-4-bromo-2-chlorobenzene 
• 197778-01-1 3-[(4-benzyloxy-3-chloro-phenyl)-hydroxy-methyl]-1-oxa-4-aza-spiro[4.5]decane-4-carboxylic acid tert-butyl ester 
• 220214-80-2 (S)-3-[(S)-(4-Benzyloxy-3-chloro-phenyl)-hydroxy-methyl]-1-oxa-4-aza-spiro[4.5]decane-4-carboxylic acid tert-butyl ester 

Downstream Products

• 197778-02-2 (2S,3R)-3-acetoxy-3-(4-benzyloxy-3-chlorophenyl)-2-tert-butoxycarbonylaminopropan-1-ol 
• 197777-87-0 (2R,3R)-3-(4-benzyloxy-3-chlorophenyl)-2-tert-butoxycarbonylamino-3-hydroxypropionic acid 
• 197778-03-3 (2R,3R)-3-Acetoxy-3-(4-benzyloxy-3-chloro-phenyl)-2-tert-butoxycarbonylamino-propionic acid 
• 197777-96-1 ((1R,2R)-2-(tert-Butyl-dimethyl-silanyloxy)-2-(3-chloro-4-hydroxy-phenyl)-1-{(S)-2-cyano-1-[(R)-1-(3-fluoro-4-nitro-phenyl)-2-methoxy-ethylcarbamoyl]-ethylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester 
• 197778-04-4 (2R,3R)-3-(4-Benzyloxy-3-chloro-phenyl)-2-tert-butoxycarbonylamino-3-(tert-butyl-dimethyl-silanyloxy)-propionic acid 
• 197777-88-1 (2R,3R)-2-tert-Butoxycarbonylamino-3-(tert-butyl-dimethyl-silanyloxy)-3-(3-chloro-4-hydroxy-phenyl)-propionic acid 

Relevant academic research and scientific papers

A new stereoselective synthetic strategy for β-hydroxy-α-amino acids of vancomycin

The synthesis of syn and anti β-hydroxy-α-amino acids representing rings C and E of vancomycin has been achieved starting from (R)- and (S)Garner's aldehydes by a stereocontrolled Grignard arylation reaction.

S(N)Ar macrocyclisation: A new approach towards the synthesis of D-O-E- segment of vancomycin

A new approach towards the synthesis of D-O-E- segment of vancomycin by S(N)Ar macrocyclisation is described.