168910-48-3

Upstream product

• 35213-00-4 2,6-dinitrobenzonitrile 
• 106-54-7 p-Chlorothiophenol 
• 593-85-1 diguanidine carbonate 
• 175204-12-3 2-(4-chlorophenylsulfanyl)-6-fluorobenzonitrile 
• 168910-81-4 2-(4-Chloro-phenylsulfanyl)-6-nitro-benzonitrile 
• 29671-92-9 chloroformamidine hydrochloride 
• 168910-67-6 2-Amino-6-(4-chloro-phenylsulfanyl)-benzonitrile 

Relevant academic research and scientific papers

2,4-DIAMINOQUINAZOLINES FOR SPINAL MUSCULAR ATROPHY

2,4-Diaminoquinazolines of formulae I-IV and VI (I, II, III, IV and VI) are useful for treating spinal muscular atrophy (SMA).

Methods of modulating serine/thereonine protein kinase function with quinazoline-based compounds

The present invention is directed in part towards methods of modulating the function of serine/threonine protein kinases with quinazoline-based compounds. The methods incorporate cells that express a serine/threonine protein kinase, such as RAF. In additi

Selective inhibitors of Candida albicans dihydrofolate reductase: Activity and selectivity of 5-(arylthio)-2,4-diaminoquinazolines

The recent increase in fungal infections, especially among AIDS patients, has resulted in the need for more effective antifungal agents. In our search for such agents, we focused on developing compounds which inhibit fungal dihydrofolate reductase (DHFR).