168975-75-5 Usage
General Description
2-chloro-4-cyclopropylpyridine is a chemical compound with the molecular formula C8H7ClN. It is a halogenated pyridine and contains a cyclopropyl group. 2-chloro-4-cyclopropylpyridine is used primarily in the pharmaceutical industry as an intermediate in the synthesis of various organic compounds, including pharmaceutical drugs. Its cyclopropyl functionality makes it a valuable building block for the modification of organic molecules, and its halogenation adds versatility to its use in chemical reactions. The chemical and physical properties of 2-chloro-4-cyclopropylpyridine make it a useful reagent in the production of pharmaceuticals and other organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 168975-75-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,8,9,7 and 5 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 168975-75:
(8*1)+(7*6)+(6*8)+(5*9)+(4*7)+(3*5)+(2*7)+(1*5)=205
205 % 10 = 5
So 168975-75-5 is a valid CAS Registry Number.
168975-75-5Relevant articles and documents
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Page/Page column 72, (2018/09/08)
Provided are compounds of Formulas (I'), (I), (II') and (II), or pharmaceutically acceptable salts thereof, and methods for their use and production.
Chemoselective sp 2-sp3 cross-couplings: Iron-catalyzed alkyl transfer to dihaloaromatics
Malhotra, Sushant,Seng, Pamela S.,Koenig, Stefan G.,Deese, Alan J.,Ford, Kevin A.
supporting information, p. 3698 - 3701 (2013/08/23)
The chemoselective functionalization of a range of dihaloaromatics with methyl, cyclopropyl, and higher alkyl Grignard reagents via iron-catalyzed cross-coupling is described. The site selectivity of C-X (X = halogen) activation is determined by factors such as the position of the halogen on the ring, the solvent, and the nucleophile. A one-pot protocol for the chemoselective synthesis of mixed dialkyl heterocycles is achieved solely employing iron catalysis.
