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16898-52-5 Usage


1,3-Bis(4-piperidyl)propane, also known as 4,4'-Trimethylenedipiperidine, is an organic compound that serves as a key monomer in the synthesis of various polymers and frameworks. It possesses a unique structure with two piperidine rings connected by a trimethylene bridge, which allows for versatile chemical reactions and applications.


Used in Polymer Synthesis:
1,3-Bis(4-piperidyl)propane is used as a monomer in the synthesis of hyperbranched copolymers from commercially available monomers such as divinylsulfone, 4,4'-trimethylenedipiperidine, and N-ethylenediamine. These copolymers have potential applications in various fields due to their unique properties, such as high molecular weight, low polydispersity, and tunable functionalities.
Used in Cadmium-Organic Frameworks:
1,3-Bis(4-piperidyl)propane is used as a building block in the synthesis of twoand three-dimensional cadmium-organic frameworks. These frameworks have potential applications in gas storage, catalysis, and sensing due to their high porosity, tunable pore sizes, and functionalizable surfaces.
Used in Polythioamide Formation:
1,3-Bis(4-piperidyl)propane undergoes the Willgerodt-Kindler reaction, a one-pot polycondensation with dialdehydes in the presence of sulfur, to form polythioamides. These polythioamides have potential applications in various fields, such as pharmaceuticals, materials science, and chemical sensors, due to their unique properties, such as high thermal stability, good film-forming ability, and tunable chemical reactivity.

Flammability and Explosibility


Check Digit Verification of cas no

The CAS Registry Mumber 16898-52-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,8,9 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 16898-52:
155 % 10 = 5
So 16898-52-5 is a valid CAS Registry Number.

16898-52-5 Well-known Company Product Price

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  • Alfa Aesar

  • (L20442)  1,3-Bis(4-piperidinyl)propane, 97+%   

  • 16898-52-5

  • 25g

  • 300.0CNY

  • Detail
  • Alfa Aesar

  • (L20442)  1,3-Bis(4-piperidinyl)propane, 97+%   

  • 16898-52-5

  • 100g

  • 798.0CNY

  • Detail
  • Aldrich

  • (121207)  4,4′-Trimethylenedipiperidine  97%

  • 16898-52-5

  • 121207-100G

  • 875.16CNY

  • Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017


1.1 GHS Product identifier

Product name 1,3-Bis(4-piperidyl)propane

1.2 Other means of identification

Product number -
Other names Piperidine, 4,4‘-(1,3-propanediyl)bis-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Intermediates
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16898-52-5 SDS

16898-52-5Related news

Molecular structure and vibrational spectra of 1,3-bis(4-piperidyl)propane by quantum chemical calculations08/04/2019

The infrared and Raman spectra of 1,3-bis(4-piperidyl)propane molecule have been recorded between 4000–400 cm−1 region and 3500–150 cm−1 region, respectively. The vibrational frequencies of the molecule are investigated. The molecular geometry and vibrational frequencies of 1,3-bis(4-piperidyl...detailed

16898-52-5Relevant articles and documents

A novel negative-working photoimaging material based on a base-amplifying silicone resin tethering phenylsulfonylethyl groups

Inoue, Satoru,Arimitsu, Koji,Abe, Yoshimoto,Ichimura, Kunihiro

, p. 1308 - 1309 (2007)

We have developed a base-sensitive silicone resin tethering phenylsulfonylethyl units as base-amplifying groups showing high thermal stability. The resin underwent a base proliferation reaction autocatalytically to generate amino groups on its side chains, which accelerated the base-catalyzed hydrolytic condensation of residual ethoxysilyl units in its main chain. Furthermore, a film of the resin sensitized with a photobase generator provided a negative-working photoimaging material with a high sensitivity. Copyright

Preparation of esters of phosphorus acids


, (2008/06/13)

Esters of phosphorus acids are prepared by an improved process whereby aromatic alcohols and phosphorus halides are reacted at specified temperatures in the presence of amine catalysts thereby providing high yields of substantially pure esters and allowing preparation of selected halogen-containing mono- and di-esters of phosphorus acids wherein halogen is directly bonded to phosphorus having substantially no side reactant contamination. The phosphorus esters are useful as intermediates in the preparation of plasticizers, oil additives and functional fluids.

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