169052-23-7

Usage

Uses

Used in Pharmaceutical Industry:
Phosphonic acid, [4-(diphenylphosphino)phenyl]-, diethyl ester is used as a catalyst in the production of pharmaceuticals. It aids in various chemical reactions, contributing to the synthesis of a wide range of medications.
Used in Agrochemical Industry:
In the agrochemical industry, Phosphonic acid, [4-(diphenylphosphino)phenyl]-, diethyl ester serves as a catalyst for the synthesis of various agrochemicals. Its application helps in the production of effective and efficient products for agricultural use.
Used in Fine Chemicals Production:
Phosphonic acid, [4-(diphenylphosphino)phenyl]-, diethyl ester is utilized as a catalyst in the synthesis of fine chemicals. Its presence in the reaction process ensures the production of high-quality specialty chemicals.
Used in Polymer and Plastics Manufacturing:
Phosphonic acid, [4-(diphenylphosphino)phenyl]-, diethyl ester is also used in the manufacture of polymers, plastics, and other industrial products. Its role as a catalyst in the production process contributes to the creation of various materials with specific properties for different applications.

Upstream product

• 762-04-9 phosphonic acid diethyl ester 
• 734-59-8 (4-bromophenyl)diphenylphosphane 
• 310-40-7 diethyl (4-fluorophenyl)phosphonate 
• 15475-27-1 potassium diphenylphosphine 
• 589-87-7 1,4-bromoiodobenzene 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 829-85-6 diphenylphosphane 
• 814-49-3 diethyl chlorophosphate 

Downstream Products

• 182625-44-1 4-(diphenylphosphinyl)phenylphosphonic acid 
• 442655-17-6 PdCl₂((C₆H₅)2PC₆H₄PO(OCH₂CH₃)2)2*CH₂Cl₂ 
• 192381-03-6 (4-diethylphosphono)phenyl-diphenylphosine-borane 
• 267876-51-7 [PtCl₂((C₆H₅)2PC₆H₄PO(OC₂H₅)2)2] 
• 267876-51-7 PtCl₂((C₆H₅)2PC₆H₄PO(OCH₂CH₃)2)2 
• 267876-56-2 [PdCl₂((C₆H₅)2PC₆H₄PO(OC₂H₅)2)2] 
• 267876-56-2 [PdCl₂((C₆H₅)2PC₆H₄PO(OC₂H₅)2)2] 

Relevant academic research and scientific papers

The First Examples of an Aryl Ring Substituted by Both Phosphine and Phosphonate Moieties: Synthesis and Characterization of the New Highly Water-soluble Phosphine Ligand Na2*1.5H2O and Platinum(II) Complexes

The highly water-soluble phosphine Na2*1.5H2O (TPPMP = 'triphenylphosphine monophosphonate') represents the first example of a compound containing an aryl ring which is substituted by both phosphine and anionic phosphonate moieties; the preparation

X-ray crystal structures of novel platinum(II) and palladium(II) complexes of dialkyl phosphonated phosphines

Two diethyl phosphonated phosphine ligands of formula Ph2P(CH2)3PO3Et2 (ligand L) and Ph2P(4-C6H4PO3Et2) (ligand L′) were used to prepare different complexes of platinum(II) (1, cis-PtCl2L2; 2, trans-PtCl2L2·H2O; 3A and 3B, cis- and trans-PtCl2L2′) and palladium(II) (4, [PdCl2L]2; 5, trans-PdCl2L2·H2O; 6, trans-PdCl2L2′·Ch2 Cl2). The single-crystal X-ray structure analyses of complexes 1, 2, 4-6 indicate that complexation involved only the phosphine end, whereas the strong polarization of the P=O bond was highlighted by the formation of hydrogen bonds with a water molecule in 2 and 5, and with a dichloromethane molecule in 6, with an exceptionally short C-H(triple dot sign)O hydrogen bond length (C(triple dot sign)O separation 3.094(3) A?).

Novel Syntheses of Mono- and Bisphosphonated Aromatic Phosphanes by Consecutive Pd-Catalyzed P-C Coupling Reactions and Nucleophilic Phosphanylation - X-ray Structure of Ph2P-C6H4-m-PO3Na2 · 5.5 H2O · iPrOH

The triphenylphosphane derivatives 2a and 5, bearing one and two phosphonic ester groups, are accessible in high yields by consecutive Pd-catalyzed P-C coupling reactions of p-bromoiodobenzene with Ph2PH and PhPH2, respectively, and then with diethyl phosphite. Ester hydrolysis yields the highly water-soluble sodium salts of mono- and bisphosphonated triphenylphosphane, 3a and 6, respectively. On reaction of the p- and m-fluorophenylphosphonic diethyl esters 7a, 7b with Ph2PK and subsequent ester hydrolysis the isomeric disodium (diphenylphosphano)phenylphosphonates 3a, 3b were obtained. The X-ray structure of Ph2P(C6H4-m-PO3Na2) · 5.5 H2O · iPrOH (space group Cmc21) has been determined. In the solid state, it forms a layer structure with hydrophilic (PO32-, H2O, iPrOH) and hydrophobic (Ph2P) compartments, in which the PO32- anionic groups are not engaged in coordination of the sodium cations.

Palladium complexes supported on hybrid organic-inorganic zirconium phosphite: Selectivity in the Heck reaction

Supported palladium complex on zirconium phosphite-phosphonate was made from triphenylphosphine phosphonic acid. The supported catalyst showed significant selectivity in the competitive Heck reaction between iodobenzene and different iodobenzoates. The re