16909-78-7

Basic information

• Product Name: 2-hydroxy-4-(2-hydroxyethoxy)benzophenone
• Synonyms: 2-hydroxy-4-(2-hydroxyethoxy)benzophenone;Benzophenone, 2-hydroxy-4-(2-hydroxyethoxy)-;Einecs 240-958-9;Methanone, (2-hydroxy-4-(2-hydroxyethoxy)phenyl)phenyl-;[2-hydroxy-4-(2-hydroxyethoxy)phenyl]-phenylmethanone
• CAS NO: 16909-78-7
• Molecular Formula: C₁₅H₁₄O₄
• Molecular Weight: 258.26926
• EINECS: 240-958-9
• Mol File: 16909-78-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 92 °C
• Boiling Point: 445.456 °C at 760 mmHg
• Flash Point: 168.605 °C
• Appearance: /
• Density: 1.266 g/cm³
• Vapor Pressure: 1.02E-08mmHg at 25°C
• Refractive Index: 1.61
• PKA: 7.48±0.35(Predicted)
• CAS DataBase Reference: 2-hydroxy-4-(2-hydroxyethoxy)benzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-4-(2-hydroxyethoxy)benzophenone(16909-78-7)
• EPA Substance Registry System: 2-hydroxy-4-(2-hydroxyethoxy)benzophenone(16909-78-7)

Safety Data

• Hazardous Substances Data: 16909-78-7(Hazardous Substances Data)

Usage

Preparation

Preparation by reaction of ethylene chlorohydrin (2-chloroethanol) with resbenzophenone, ? in the presence of sodium hydroxide, in boiling water for 6 h (40%) or in water at 70° for 18 h (91%); ? in the presence of sodium carbonate in refluxing dilute ethanol for 16 h (58%).

InChI:InChI=1/C15H14O4/c16-8-9-19-12-6-7-13(14(17)10-12)15(18)11-4-2-1-3-5-11/h1-7,10,16-17H,8-9H2

Upstream product

• 131-56-6 2.4-dihydroxybenzophenone 
• 107-07-3 2-chloro-ethanol 
• 16432-81-8 2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate 
• 96-49-1 [1,3]-dioxolan-2-one 
• 57-09-0 cetyltrimethylammonim bromide 

Downstream Products

• 21112-75-4 2-Hydroxy-4-<β-(2,4,6-tribrom-phenoxymethoxy)-ethoxy>-benzophenon 
• 21112-70-9 4-<β-(Chlormethoxy)-ethoxy>-2-hydroxy-benzophenon 
• 21112-80-1 2-Hydroxy-4-<β-(pentachlor-phenoxymethoxy)-ethoxy>-benzophenon 

Relevant articles and documents

UV ABSORBING OCULAR LENS

Ocular lenses having UV absorbing properties are disclosed. The ocular lens comprises a hydrogel polymer comprising polymerised residues derived from a polymerisable UV absorber of formula (I): U-L-Py (I) wherein: U is a UV absorbing moiety; L is a hydrophilic non-polyalkylene glycol linker comprising an anionic, a zwitterionic or a saccharide moiety; and Py is an ethylenically unsaturated polymerisable moiety.

Process for the preparation of 2-hydroxy-4-(2'-hydroxyethoxy) benzophenones

A process for the preparation of 2-hydroxy-4-(2'-hydroxyethoxy)benzophenones, by reacting 2,4-dihydroxybenzophenones with ethylene carbonate in the presence of a quaternary ammonium salt catalyst at elevated temperatures, and isolating the finished product from the crude reaction mixture.