16909-78-7

Usage

Preparation

Preparation by reaction of ethylene chlorohydrin (2-chloroethanol) with resbenzophenone, ? in the presence of sodium hydroxide, in boiling water for 6 h (40%) or in water at 70° for 18 h (91%); ? in the presence of sodium carbonate in refluxing dilute ethanol for 16 h (58%).

InChI:InChI=1/C15H14O4/c16-8-9-19-12-6-7-13(14(17)10-12)15(18)11-4-2-1-3-5-11/h1-7,10,16-17H,8-9H2

Upstream product

• 131-56-6 2.4-dihydroxybenzophenone 
• 107-07-3 2-chloro-ethanol 
• 96-49-1 [1,3]-dioxolan-2-one 
• 57-09-0 cetyltrimethylammonim bromide 
• 16432-81-8 2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate 

Downstream Products

• 21112-80-1 2-Hydroxy-4-<β-(pentachlor-phenoxymethoxy)-ethoxy>-benzophenon 
• 21112-70-9 4-<β-(Chlormethoxy)-ethoxy>-2-hydroxy-benzophenon 
• 21112-75-4 2-Hydroxy-4-<β-(2,4,6-tribrom-phenoxymethoxy)-ethoxy>-benzophenon 

Relevant academic research and scientific papers

UV ABSORBING OCULAR LENS

Ocular lenses having UV absorbing properties are disclosed. The ocular lens comprises a hydrogel polymer comprising polymerised residues derived from a polymerisable UV absorber of formula (I): U-L-Py (I) wherein: U is a UV absorbing moiety; L is a hydrophilic non-polyalkylene glycol linker comprising an anionic, a zwitterionic or a saccharide moiety; and Py is an ethylenically unsaturated polymerisable moiety.

Benzophenone derivative, ultraviolet absorbent and external preparation for skin

Benzophenone derivatives expressed by the following general expression (1): wherein A in the above general expression (1) is a residual group obtained by removing one hydroxyl group from sugar or sugar alcohol, and B is a benzophenone group shown by the following general expression (2) STR1 wherein R1 through R10 each is expressed by hydrogen, hydroxyl group, an alkoxy group, or the aforesaid binder C, and at least one of them is the binder C. In the case of an alkoxy group, preferably the number of carbon atoms is 1 to 4. C is equivalent to --O--R-- (O is oxygen, R is a fatty chain, and the number of carbon atoms therein is preferably 1 to 4), or 1 mole of glycerin with one hydroxyl group therein bound to A and another hydroxyl group to B. The benzophenone derivatives according to the present invention have excellent capability to absorb ultraviolet rays as well as high compatibility with polar solvent. Also the external preparation for skin in which the benzophenone derivatives are mixed can be mixed in a polar base with wide availability for industrial purpose.

Process for the preparation of 2-hydroxy-4-(2'-hydroxyethoxy) benzophenones

A process for the preparation of 2-hydroxy-4-(2'-hydroxyethoxy)benzophenones, by reacting 2,4-dihydroxybenzophenones with ethylene carbonate in the presence of a quaternary ammonium salt catalyst at elevated temperatures, and isolating the finished product from the crude reaction mixture.