169125-18-2

Upstream product

• 169125-12-6 (+)-(4S,5R)-1,5-dimethyl-4-phenyl-3-(4-methoxyphenylacetyl)-2-imidazolidinone 
• 73406-52-7 2-O-methoxymethylbenzyl bromide 
• 169125-15-9 (+)-(4S,5R)-1,5-dimethyl-4-phenyl-3-<2'-(4-methoxyphenyl)-3'-(2-O-methoxymethylphenyl)>propionyl-2-imidazolidinone 

Downstream Products

• 169125-21-7 2-[(S)-3-Hydroxy-2-(4-methoxy-phenyl)-propyl]-phenol 

Relevant academic research and scientific papers

Stereoselective synthesis of isoflavonoids. (R)- and (S)-isoflavans

α-Benzylation of (+)- and (-)-N-phenylacetyl imidazolidinones with 2- O-methoxy-methylbenzyl bromides, followed by reductive removal of the chiral auxiliary and cyclization, afforded oxygenated isoflavans in excellent enantiomeric excess and yield.

The First Enantioselective Synthesis of Isoflavanoids: (R)- and (S)-Isoflavans

α-Benzylation of (+)- and (-)-N-phenylacetyl imidazolidinones with 2-O-methoxymethylbenzyl bromide, followed by reductive removal of the chiral auxiliary and cyclization, leads to isoflavans in excellent enantiomeric excess and yield.