73406-52-7

Upstream product

• 55359-65-4 1-methoxymethoxy-2-methylbenzene 
• 69-72-7 salicylic acid 
• 119-36-8 methyl salicylate 
• 27701-23-1 methyl 2-(methoxymethyloxy)benzoate 
• 90-02-8 salicylaldehyde 
• 5533-04-0 2-(methoxymethoxy)benzaldehyde 
• 89-95-2 2-methyl-benzyl alcohol 
• 95-48-7 ortho-cresol 
• 73406-54-9 (2-Methoxymethoxyphenyl)methyl-methansulfonat 
• 5533-05-1 (2-methoxymethoxyphenyl)methanol 

Downstream Products

• 152955-18-5 methyl 2-(4-methoxyphenyl)-3-(2-O-methoxymethylphenyl)propanoate 
• 152955-17-4 methyl 2-(2-methoxyphenyl)-3-(2-O-methoxymethylphenyl)propanoate 
• 110983-36-3 o-methoxymethoxybenzyltriphenylphosphonium bromide 
• 152955-16-3 methyl 3-(2-O-methoxymethylphenyl)-2-phenylpropanoate 
• 169125-15-9 (+)-(4S,5R)-1,5-dimethyl-4-phenyl-3-<2'-(4-methoxyphenyl)-3'-(2-O-methoxymethylphenyl)>propionyl-2-imidazolidinone 
• 169125-26-2 (-)-(4R,5S)-1,5-dimethyl-4-phenyl-3-<2'-(4-methoxyphenyl)-3'-(2-O-methoxymethylphenyl)>propionyl-2-imidazolidinone 
• 213970-19-5 methyl 2-(3,4-dimethoxyphenyl)-3-(2-O-methoxymethylphenyl)propanoate 
• 213970-22-0 methyl 2-(2,4-dimethoxyphenyl)-3-(2-O-methoxymethylphenyl)propanoate 
• 225089-98-5 (-)-(4R,5S)-1,5-dimethyl-4-phenyl-3-<2'-(3,4-dimethoxyphenyl)-3'-(2-O-methoxymethylphenyl)>propionyl-2-imidazolidinone 
• 225089-84-9 (+)-(4S,5R)-1,5-dimethyl-4-phenyl-3-<2'-(3,4-dimethoxyphenyl)-3'-(2-O-methoxymethylphenyl)>propionyl-2-imidazolidinone 
• 225089-99-6 (-)-(4R,5S)-1,5-dimethyl-4-phenyl-3-<2'-(2,4-dimethoxyphenyl)-3'-(2-O-methoxymethylphenyl)>propionyl-2-imidazolidinone 
• 225089-85-0 (+)-(4S,5R)-1,5-dimethyl-4-phenyl-3-<2'-(2,4-dimethoxyphenyl)-3'-(2-O-methoxymethylphenyl)>propionyl-2-imidazolidinone 
• 289472-10-2 2-[(Z)-4-(2-Methoxymethoxy-phenyl)-2-methyl-but-2-enyloxy]-tetrahydro-pyran 
• 752209-20-4 2-(3-methylocta-2,7-dienyl)phenyl methoxymethyl ether 

Relevant academic research and scientific papers

Regioselective Fluorination of Acenes: Tailoring of Molecular Electronic Levels and Solid-State Properties

Optoelectronic properties of molecular solids are important for organic electronic devices and are largely determined by the adopted molecular packing motifs. In this study, we analyzed such structure-property relationships for the partially regioselectiv

BITTER TASTE MODULATORS

The present invention includes antagonists of human type 2 taste receptors (hT2Rs) having structural Formula (I). The present invention also provides compositions containing these antagonists, the use of these antagonists for modulating taste perception, particularly bitter taste, and the method of preparing these antagonists (I).

Hydrogen-atom abstraction/cyclization in synthesis. Direct syntheses of coumestan and coumestrol

The synthesis of coumestrol has been achieved in five steps from 1,3-dimethoxybenzene. The key step is a photochemical cyclization of a glyoxylate ester.

A new preparation of 2,5-dihydro-1-benzoxepins using Mitsunobu cyclization, and the synthesis of natural radulanins

Mitsunobu cyclization of o-[4-hydroxy-3-methyl-2(Z)-butenyl]phenol 2a effected selective seven-membered cyclization to give 3-methyl-2,5-dihydro-1- benoxepin 1a. Using this procedure, natural radulanin A and radulanin A methyl ether were synthesized effec

The direct synthesis of isoflavans VIA α-alkylation of phenylacetates

Deprotonation of oxygenated phenylacetates and quenching of the enolates with oxygenated benzylic electrophiles, afforded 2,3-diarylpropanoates which served as precursors to the isoflavans following consecutive reduction and cyclization steps.

N-(3-pyridylalkyl)sulfonamide compounds which have useful pharmaceutical activity

Illustrative examples of the N-(3-pyridylalkyl)sulfonamide derivative are represented by the following formulae [II] and [III]: STR1 The derivatives are available for a thromboxane A2 production inhibitor, a thromboxane A2 antagonist, a prostaglandin H2 antagonist, an anti-thrombus agent, a thrombus-preventing agent and an anti-allergy agent.

THE FIRST DIRECT SYNTHESIS OF ISOFLAVANS VIA α-ALKYLATION OF PHENYLACETATES

Deprotonation of phenylacetates and quenching of the enolates with benzylic electrophiles, afford 2,3-diarylpropanoates which serve as precursors to isoflavans following consecutive reduction and cyclization steps.

Preparation of (E)-2-Hxdroxy-4'-Substituted Stilbenes

Sixteen (E)-2-hydroxy-4'-substituted stilbenes have been prepared by the Wittig reaction.Direct coupling of the appropriate p-substituted benzylidenetriphenylphosphoranes with salicylaldehyde afforded the (E)-stilbenols (2) 4'-R = H(2a), Me(2b), But(2c), Ph(2d), CN(2e), NO2(2i), OMe(2k), F(2n), Cl(2o), and Br(2p).Alternatively, the Wittig reaction of o-methoxymethoxybenzylidenetriphenylphosphorane with various p-substituted benzaldehydes gave the (E)-methoxymethylstilbenols (4) which upon acidic cleavage furnished the corresponding stilbenols (2) 4'-R = CN(2e), CO2Me(2f), NMe2(2h), OH(2j), OAc(2m), and I(2q).The symmetrical (E)-2,2'-dihydroxystilbene was obtained in an analogous fashion.Reduction of nitrostilbenol (2i) yielded the corresponding aminostilbenol (2g).

Synthesis and hydrolysis kinetics of 4-cyano-4-phenylpiperidine derivatives: A route to morphine analogs

A description is given of a high-yield synthesis leading to various hydroxy-2 phenylacetonitriles and to various benzodihydro-2,3 furannones-2. The intermediary 12 benzylic mesylates give quantitatively the corresponding 11 chlorides by the action of hydrochlorate of triethylamine; this procedure constitutes a very rewarding and easy method for chlorinating the benzylic alcohols in two stages without isolating the intermediary. A proximate effect has been shown which makes possible the hydrolysis of certain phenylacetonitriles by dilute acetic acid. This hydrolysis becomes very rapid when these nitriles are distributed; the increase of the speed of the hydrolysis illustrates the gem dialkyle effect.