169129-75-3Relevant academic research and scientific papers
Nb-benzoyltryptamine derivatives with relaxant activity in guinea-pig ileum
Gutierrez, Stanley Juan C.,Claudino, Fladmir De S.,Da Silva, Bagnolia A.,Camara, Celso A.,De Almeida, Reinaldo N.,De Souza, Maria De Fatima V.,Da Silva, Marcelo S.,Da-Cunha, Emidio V.L.,Barbosa-Filho, Jos Maria
, p. 475 - 477 (2007/10/03)
A series of derivatives analogous to Nb-benzoyltryptamine were synthesized by the Schotten-Bauman procedure. The products obtained were: N b-4-methoxy-benzoyltryptamine, Nb-2,4-dimethoxy- benzoyltryptamine, Nb-3
Mannich biscyclizations. Total synthesis of (-)-ajmalicine
L?gers, Michael,Overman, Larry E.,Welmaker, Gregory S.
, p. 9139 - 9150 (2007/10/02)
A concise enantioselective total synthesis of the cardiovascular agent (-)-ajmalicine and an approach toward the synthesis of (+)-19-epiajmalicine are described. The key step of the (-)-ajmalicine synthesis is a carboxylate-terminated N-acyliminium ion biscyclization (74 → 67), which assembles the D and E rings of this heteroyohimbine alkaloid in one step. A related carboxylate-terminated iminium ion biscyclization (28 → 29) is the central step in the approach to (+)-epiajmalicine.
