1692-02-0

Basic information

• Product Name: (4-FLUORO-BENZYL)-PYRIDIN-2-YL-AMINE DIHYDROCHLORIDE
• Synonyms: (4-FLUORO-BENZYL)-PYRIDIN-2-YL-AMINE DIHYDROCHLORIDE;N-(4-Fluorobenzyl)pyridin-2-aMine dihydrochloride
• CAS NO: 1692-02-0
• Molecular Formula: C₁₂H₁₁FN₂
• Molecular Weight: 275.1494232
• Mol File: 1692-02-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 326.6±22.0 °C(Predicted)
• Appearance: /
• Density: 1.210±0.06 g/cm3(Predicted)
• PKA: 6.21±0.10(Predicted)
• CAS DataBase Reference: (4-FLUORO-BENZYL)-PYRIDIN-2-YL-AMINE DIHYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-FLUORO-BENZYL)-PYRIDIN-2-YL-AMINE DIHYDROCHLORIDE(1692-02-0)
• EPA Substance Registry System: (4-FLUORO-BENZYL)-PYRIDIN-2-YL-AMINE DIHYDROCHLORIDE(1692-02-0)

Safety Data

• Hazardous Substances Data: 1692-02-0(Hazardous Substances Data)

Usage

General Description

(4-Fluoro-benzyl)-pyridin-2-yl-amine dihydrochloride is a compound that consists of a pyridine ring linked to a (4-fluoro-benzyl) group. This chemical is commonly used in organic synthesis and medicinal chemistry as a building block for the creation of various pharmaceuticals and biologically active molecules. The dihydrochloride salt form of this compound makes it more stable and easier to handle in laboratory settings. Its ability to modify the structure and function of biomolecules makes it useful for drug discovery and development, particularly in the treatment of neurological disorders and infectious diseases. Additionally, it is used as a reagent in chemical reactions to introduce the (4-fluoro-benzyl) and pyridin-2-yl-amine groups into molecules for further functionalization.

Upstream product

• 372-48-5 2-fluoropyridine 
• 140-75-0 para-fluorobenzylamine 
• 504-29-0 2-aminopyridine 
• 352-11-4 1-chloromethyl-4-fluorobenzene 
• 104-87-0 4-methyl-benzaldehyde 
• 459-56-3 4-fluorobenzylic alcohol 
• 459-57-4 4-fluorobenzaldehyde 
• 462-08-8 pyridin-3-ylamine 
• 1445435-43-7 C₁₇H₁₉FN₂O₂ 
• 38427-94-0 N-(tert-butoxycarbonyl)-2-aminopyridine 

Downstream Products

• 396-59-8 N-(4-fluoro-benzyl)-N',N'-dimethyl-N-[2]pyridyl-ethylenediamine 
• 136343-75-4 8-fluoropyrido[1,2-a]benzimidazole 
• 1039803-54-7 (5-bromo-pyridin-2-yl)-(4-fluoro-benzyl)-amine 

Relevant articles and documents

Isoxazole-containing pyridopyrimidinone compound as well as preparation method and application thereof

The invention relates to an isoxazole-containing pyridinopyrimidinone compound as well as a preparation method and application thereof. The compound disclosed by the invention has a structure shown as a formula (I), has excellent insecticidal activity on sogatella furcifera, brown planthopper and the like, and can be used for medicines or agents for preventing and treating hemiptera pests such as rice planthoppers and aphids. The structure and the preparation process are simple, and the production cost is low.

Co(II) PCP Pincer Complexes as Catalysts for the Alkylation of Aromatic Amines with Primary Alcohols

Efficient alkylations of amines by alcohols catalyzed by well-defined Co(II) complexes are described that are stabilized by a PCP ligand (N,N′-bis(diisopropylphosphino)-N,N′-dimethyl-1,3-diaminobenzene) based on the 1,3-diaminobenzene scaffold. This reaction is an environmentally benign process implementing inexpensive, earth-abundant nonprecious metal catalysts and is based on the acceptorless alcohol dehydrogenation concept. A range of primary alcohols and aromatic amines were efficiently converted into mono-N-alkylated amines in good to excellent isolated yields.

A mild method for the regioselective bromination of 2-aminopyridines

An efficient and regioselective bromination of 2-aminopyridines was developed. The environmental friendly bromination occurs under mild and clean conditions using readily available 1-butylpyridinium bromide as the bromine source and hydrogen peroxide as the green oxidant.