169208-89-3

Upstream product

• 772315-74-9 (-)-(1S,2S,3'S)-1-Phenyl-2-(1'-phenylhept-1'-in-3'-ylamino)propan-1,3-diol 
• 2579-22-8 Phenylpropargyl aldehyde 
• 169274-92-4 ((4S,5S)-2,2-Dimethyl-4-phenyl-[1,3]dioxan-5-yl)-[3-phenyl-prop-2-yn-(E)-ylidene]-amine 

Downstream Products

• 147722-51-8 (+)-(S)-1-Phenylhept-1-in-3-ylamin 

Relevant academic research and scientific papers

Enantioselektive Synthese von Allyl-, Propargyl- und 4-En-2-inyl-aminen durch 1,2-Addition von Organocer-Reagenzien an chirale Aldimine

(E)- and (Z)-Allyl-, propargyl, and 4-en-2-ynyl-amines 5 and 14, useful bifunctional building blocks and of pharmaceutical interest, are synthesized in high enantiomeric purity (e.e. >/= 97 percent).Key step is the diastereoselective 1,2-addition (d.e. 86

Enantioselective Synthesis of Allyl- and Propargylamines via Nucleophilic 1,2-Addition to Chiral Aldimines

The asymmetric synthesis of allylamines and propargylamines 5 in high enantiomeric purity (e.e >/= 97percent) is described.Key step is the 1,2-addition of organocerium reagents to chiral α,β-unsaturated aldimines 3 to produce secondary amines 4.The chiral