169229-06-5

Basic information

• Product Name: 3-Pyridinecarbonyl chloride, 2-methyl- (9CI)
• Synonyms: 3-Pyridinecarbonyl chloride, 2-methyl- (9CI)
• CAS NO: 169229-06-5
• Molecular Formula: C₇H₆ClNO
• Molecular Weight: 155.58164
• Product Categories: ACIDHALIDE
• Mol File: 169229-06-5.mol
• Article Data: 19

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Pyridinecarbonyl chloride, 2-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarbonyl chloride, 2-methyl- (9CI)(169229-06-5)
• EPA Substance Registry System: 3-Pyridinecarbonyl chloride, 2-methyl- (9CI)(169229-06-5)

Safety Data

• Hazardous Substances Data: 169229-06-5(Hazardous Substances Data)

Upstream product

• 65719-09-7 methyl 2-methylnicotinate 
• 3222-56-8 2-methylnicotinic acid 

Downstream Products

• 169229-08-7 pyridocyclobuten-5-one 
• 909649-12-3 4-bromo-1-chloro-1,6-naphthyridine 
• 155057-98-0 1,2,3,4-tetrahydro-1,6-naphthyridine-5(6H)-one 
• 155057-97-9 8-bromo-5,6-dihydro-1,6-naphthyridin-5-one 
• 23616-31-1 1,6-naphthyridine-5(6H)-one 
• 1590403-10-3 C₂₁H₁₆F₄N₂O₂ 
• 1590403-06-7 C₁₉H₁₃F₃N₄O₂ 
• 1590403-04-5 C₂₁H₁₂F₄N₂O₂ 
• 1590409-70-3 C₁₅H₈BrF₃N₂O₂ 
• 1446443-01-1 2-methyl-N-[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]nicotinamide 
• 1446442-70-1 4-iodo-2-methyl-N-[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]nicotinamide 
• 1204535-44-3 (2S)-2-methyl-1-[(2-methyl-3-pyridinyl)carbonyl]-4-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine 
• 953066-24-5 N-(3-chlorophenyl)-N-((8-fluoro-2-oxo-1,2-dihydroquinolin-4-yl)methyl)-2-methylnicotinamide 
• 77594-56-0 2-methyl-N-methylnicotinamide 

Relevant articles and documents

Improved synthesis of sterically encumbered heteroaromatic biaryls from aromatic β-keto esters

A protocol for the synthesis of hindered 4-aryl 2-aminopyrimidines from β–keto esters is described. The process employs trifluoroethanol as an essential additive to promote the guanidine condensation reaction, enabling the synthesis of 25 aryl- and heteroaryl substituted aminopyrimidines in good yields and high purities with no column chromatography. The conditions described herein are readily scalable and have been employed in the large-scale synthesis of the clinical A2a/A2bR antagonist AB928.

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