Cas 169252-29-3,[4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-(4-methylsulfanyl-phenyl)-methanone

169252-29-3

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Basic information

Product Name: [4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-(4-methylsulfanyl-phenyl)-methanone
Synonyms: [4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-(4-methylsulfanyl-phenyl)-methanone
CAS NO:169252-29-3
Molecular Formula:
Molecular Weight: 461.027
EINECS: N/A
Product Categories: N/A
Mol File: 169252-29-3.mol
Article Data: 1

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: [4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-(4-methylsulfanyl-phenyl)-methanone(CAS DataBase Reference)
NIST Chemistry Reference: [4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-(4-methylsulfanyl-phenyl)-methanone(169252-29-3)
EPA Substance Registry System: [4-(8-Chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-(4-methylsulfanyl-phenyl)-methanone(169252-29-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 169252-29-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 169252-29-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,2,5 and 2 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 169252-29:
(8*1)+(7*6)+(6*9)+(5*2)+(4*5)+(3*2)+(2*2)+(1*9)=153
153 % 10 = 3
So 169252-29-3 is a valid CAS Registry Number.

169252-29-3Upstream product

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169252-29-3Relevant articles and documents

Discovery of novel nonpeptide tricyclic inhibitors of ras farnesyl protein transferase

Njoroge, F. George,Doll, Ronald J.,Vibulbhan, Bancha,Alvarez, Carmen S.,Bishop, W. Robert,Petrin, Joanne,Kirschmeier, Paul,Carruthers, Nicholas I.,Wong, Jesse K.,Albanese, Margaret M.,Piwinski, John J.,Catino, Joseph,Girijavallabhan,Ganguly, Ashit K.

, p. 101 - 113 (1997)

A comprehensive structure-activity relationship (SAR) study of novel tricyclic amides has been undertaken. The discovery of compounds that are potent FPT inhibitors in the nanomolar range has been achieved. These compounds are nonpeptidic and do not contain sulfhydryl groups. They selectively inhibit farnesyl protein transferase (FPT) and not geranylgeranyl protein transferase-1 (GGPT-1). They also inhibit H-Ras processing in Cos monkey kidney cells.

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