16927-06-3

Usage

Uses

Used in Polymer Synthesis:
2,5-bis(ethoxycarbonyl)benzene-1,4-dicarboxylic acid is used as a monomer in the production of liquid crystal polymers and polyester resins. Its incorporation into these polymers enhances their mechanical properties, thermal stability, and chemical resistance, making them suitable for various applications in the plastics and coatings industries.
Used in Drug Delivery Systems:
2,5-bis(ethoxycarbonyl)benzene-1,4-dicarboxylic acid is studied for its potential use in drug delivery systems. Its chemical structure allows for the development of novel drug carriers that can improve the solubility, bioavailability, and targeted delivery of therapeutic agents, enhancing their efficacy and reducing side effects.
Used in Organic Light-Emitting Diodes (OLEDs):
2,5-bis(ethoxycarbonyl)benzene-1,4-dicarboxylic acid is also considered as a component in the development of organic light-emitting diodes. Its unique properties contribute to the improvement of device performance, including enhanced brightness, efficiency, and stability, making it a promising material for the next generation of OLED technologies.

Upstream product

• 1036648-92-6 1,4-dibenzyl 2,5-diethyl benzene-1,2,4,5-tetracarboxylate 
• 64-17-5 ethanol 
• 89-32-7 Pyromellitic dianhydride 

Relevant academic research and scientific papers

Synthesis and self-assembly of novel hydrazide derivatives containing multi-alkoxy chains with different lengths

We report on the synthesis and self-assembly of two novel types of hydrazide derivatives, e.g. 1,4-bis[(3,4,5-trialkoxyphenyl)-dihydrazide]-2,5-diethylphthalate (C-Tn, n = 7, 10, 12 and 16) and N',N'-bis[3,4,5-tris(dodecyloxy)benzamido]-pyromellitic diimi

Esters of pyromellitic acid. Part I. Esters of achiral alcohols: Regioselective synthesis of partial and mixed pyromellitate esters, mechanism of transesterification in the quantitative esterification of the pyromellitate system using orthoformate esters, and a facile synthesis of the ortho pyromellitate diester substitution pattern

(Chemical Equation Presented) Mild conditions and reversible anhydride formation allow a relative differentiation to be made of the four equivalent carbonyl groups of pyromellitic dianhydride (PMDA, benzene-1,2,4,5- tetracarboxylic dianhydride) in esterification, leading to regioselective methods to generate a wide range of partially or totally esterified products or products bearing differing esterifying groups at the different positions. Pyromellitate monoester anhydrides form efficiently in dichloromethane/ triethylamine from 1 equiv of the alcohol. Under the same conditions, two different alcohols can be made to react sequentially. With 2 equiv of an alcohol, the usual mixture of meta and para diesters is obtained, separated by crystallization from HOAc. Meta and para dibenzyl pyromellitates served as regiospecific sources of other diesters, by further esterification followed by hydrogenolysis. Refluxing orthoformate triesters were found to effect quantitative esterification of the pyromellitate system under autocatalytic conditions; minor ester exchange with pre-existing esters (0-5% of total product) was ascribed to reversible anhydride formation. For general esterification with alcohols, partial ester acid chlorides were obtained using oxalyl chloride. Pyromellitate triesters afforded the ortho diester anhydrides upon distillation, thereby providing facile entry into the mostly novel ortho substitution pattern in this system. The requisite triesters were prepared by selective saponification or by the prior incorporation of one benzyl ester substituent, which could be removed by catalytic hydrogenolysis. The various benzyl esters of pyromellitates hydrogenolyzed smoothly to release the carboxylic acid groups without disturbance of pyromellitate aromaticity.