169274-98-0

Upstream product

• 147781-29-1 (-)-(4R,5R)-5-amino-2,2-dimethyl-4-phenyl-1,3-dioxane 
• 169274-93-5 ((4R,5R)-2,2-Dimethyl-4-phenyl-[1,3]dioxan-5-yl)-[3-phenyl-prop-2-yn-(E)-ylidene]-amine 
• 2579-22-8 Phenylpropargyl aldehyde 
• 109-72-8 n-butyllithium 
• 147722-41-6 (+)-(4R,5R)-2,2-Dimethyl-4-phenyl-N-(3'-phenylprop-2'-in-1'-yliden)-1,3-dioxan-5-amin 

Downstream Products

• 147722-52-9 (-)-(R)-1-Phenylhept-1-in-3-ylamin 
• 169208-90-6 (+)-(R)-N-(1-Phenylhept-1-in-3-yl)formamid 

Relevant academic research and scientific papers

Enantioselektive Synthese von Allyl-, Propargyl- und 4-En-2-inyl-aminen durch 1,2-Addition von Organocer-Reagenzien an chirale Aldimine

(E)- and (Z)-Allyl-, propargyl, and 4-en-2-ynyl-amines 5 and 14, useful bifunctional building blocks and of pharmaceutical interest, are synthesized in high enantiomeric purity (e.e. >/= 97 percent).Key step is the diastereoselective 1,2-addition (d.e. 86

Enantioselective Synthesis of Allyl- and Propargylamines via Nucleophilic 1,2-Addition to Chiral Aldimines

The asymmetric synthesis of allylamines and propargylamines 5 in high enantiomeric purity (e.e >/= 97percent) is described.Key step is the 1,2-addition of organocerium reagents to chiral α,β-unsaturated aldimines 3 to produce secondary amines 4.The chiral