169280-33-5

Basic information

• Product Name: A,A-DIMETHYL-4-[4-[4-(HYDROXYDIPHENYL METHYL)-1-PIPERIDINYL]-1-OXOBUTYL]PHENYL ACETIC ACID METHYL ESTER HYDROCHLORIDE
• Synonyms: A,A-DIMETHYL-4-[4-[4-(HYDROXYDIPHENYL METHYL)-1-PIPERIDINYL]-1-OXOBUTYL]PHENYL ACETIC ACID METHYL ESTER HYDROCHLORIDE;A,A-DIMETHYL-4-[4-[4-(HYDROXYDIPHENYL METHYL)-1-PIPERIDINYL]-1-OXOBUTYL]PHENYL ACETIC ACID METHYL ESTER HYDROCHLORIDE/Methyl 2-(4-(4-chlorobutanoyl)phenyl)-2-Methylpropanoate;Triazole-5-carboxylic acid analog
• CAS NO: 169280-33-5
• Molecular Formula: C₃₃H₃₉NO₄*ClH
• Molecular Weight: 550.128
• Product Categories: (intermediate of fexofenadine hcl)
• Mol File: 169280-33-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 677.2°C at 760 mmHg
• Flash Point: 363.4°C
• Appearance: /
• Vapor Pressure: 2.89E-19mmHg at 25°C
• CAS DataBase Reference: A,A-DIMETHYL-4-[4-[4-(HYDROXYDIPHENYL METHYL)-1-PIPERIDINYL]-1-OXOBUTYL]PHENYL ACETIC ACID METHYL ESTER HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: A,A-DIMETHYL-4-[4-[4-(HYDROXYDIPHENYL METHYL)-1-PIPERIDINYL]-1-OXOBUTYL]PHENYL ACETIC ACID METHYL ESTER HYDROCHLORIDE(169280-33-5)
• EPA Substance Registry System: A,A-DIMETHYL-4-[4-[4-(HYDROXYDIPHENYL METHYL)-1-PIPERIDINYL]-1-OXOBUTYL]PHENYL ACETIC ACID METHYL ESTER HYDROCHLORIDE(169280-33-5)

Safety Data

• Hazardous Substances Data: 169280-33-5(Hazardous Substances Data)

Usage

General Description

A,A-DIMETHYL-4-[4-[4-(HYDROXYDIPHENYL METHYL)-1-PIPERIDINYL]-1-OXOBUTYL]PHENYL ACETIC ACID METHYL ESTER HYDROCHLORIDE is a chemical compound with potential pharmaceutical applications. It is a hydrochloride salt of a methyl ester of A,A-dimethyl-4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]phenylacetic acid, and its structure contains a piperidine ring and a phenylacetic acid group. A,A-DIMETHYL-4-[4-[4-(HYDROXYDIPHENYL METHYL)-1-PIPERIDINYL]-1-OXOBUTYL]PHENYL ACETIC ACID METHYL ESTER HYDROCHLORIDE may have properties that make it a candidate for use as a pharmaceutical intermediate or as a chemical reagent in synthetic processes. Further research would be needed to fully understand its potential uses and effects.

InChI:InChI=1/C33H39NO4.ClH/c1-32(2,31(36)38-3)26-18-16-25(17-19-26)30(35)15-10-22-34-23-20-29(21-24-34)33(37,27-11-6-4-7-12-27)28-13-8-5-9-14-28;/h4-9,11-14,16-19,29,37H,10,15,20-24H2,1-3H3;1H

Upstream product

• 115-46-8 C₁₈H₂₁NO 
• 154477-54-0 2-[4-(4-Chloro-butyryl)-phenyl]-2-methyl-propionic acid, methyl ester 

Downstream Products

• 343255-29-8 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylbenzeneacetic acid, methyl ester hydrochloride 

Relevant articles and documents

Intermediates useful for the preparation of antihistaminic piperidine derivatives

The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula whereinW represents —C(=O)— or —CH(OH)—;R1 represents hydrogen or hydroxy;R2 represents hydrogen;R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2;n is an integer of from 1 to 5;m is an integer 0 or 1;R3 is —COOH or —COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched each of A is hydrogen or hydroxy; and pharmaceutically acceptable salts and individual optical isomers thereof,with the proviso that where R1 and R2 are taken together to form a second bond between the carbon atoms bearing R1 and R2 or where R1 represented hydroxy, m is an integer 0.