16929-83-2

Upstream product

• 675-10-5 4-hydroxy-6-methyl-2-pyron 
• 100-52-7 benzaldehyde 
• 90-02-8 salicylaldehyde 

Downstream Products

• 101614-02-2 10-phenyl-2,7-dimethyl-4,5-dioxo-3,6,9-trioxa-3,4,5,6,9,10-hexahydroanthracene 
• 51424-04-5 3,3'-(phenylmethylene)bis(4-hydroxy-6-methylpyridin-2(1H)-one) 
• 101560-47-8 3,7-dimethyl-10-phenyl-1H,9H,10H-thiopyrano[3,2-c:5,6-c']dipyran-1,9-dione 
• 101560-52-5 C₃₃H₂₈O₁₀S₂ 

Relevant academic research and scientific papers

Chemistry of 1,5-diketones: IV. New aspects of the chemistry of 1,5-Dioxo compounds of the 2H-pyran-2-one series

Reactions of 3,3′-(phenylmethanediyl)bis(4-hydroxy-6-methyl-2H-pyran-2-one) with electrophilic (PCl5, CF3COOH, BF3 · Et2O) and nucleophilic reagents (P2S5) in different solvents were studie

Synthesis of Fused 2Н-Pyridin-2-ones under the Conditions of Multicomponent Hantzsch Reaction

One-pot process was studied between a substituted 4-hydroxy-2Н-pyran-2-one and aromatic aldehydes and ammonium acetate in the conditions of modified Hantzsch reaction in acid environment under thermal and microwave activation. Arylmethylenebis-4-hydroxy-2

Variability of the Transformations of 4-Hydroxy-6-methyl-2H-pyran-2-one under Modified Biginelli Reaction Conditions

A modified version of the three-component Biginelli reaction of 4-hydroxy-6-methyl-2H-pyran-2-one with aromatic aldehydes in urea under conventional heating and microwave activation has been studied. Depending on the order of addition of the reactants, su

Application of Fe3O4@SiO2/(CH2)3-[imidazolium-SO3H]Cl as a robust, magnetically recoverable solid acid catalyst for the facile preparation of arylbispyranylmethanes

In this study, Fe3O4@SiO2/(CH2)3-[imidazolium-SO3H]Cl shows robust promoting capability in the synthesis of arylbispyranylmethane derivatives under mild and green conditions. Arylbispyranyl

Application of biological-based nano and nano magnetic catalysts in the preparation of arylbispyranylmethanes

Herein, the utilization of 2-carbamoylhydrazine-1-sulfonic acid, carbamoylsulfamic acid and their related nano magnetic core-shell catalysts were described as biological-based nano catalysts with a urea moiety in the synthesis of arylbispyranylmethane der

Merging supramolecular catalysis and aminocatalysis: Amino-appended β-cyclodextrins (ACDs) as efficient and recyclable supramolecular catalysts for the synthesis of tetraketones

Well-designed amino-appended β-cyclodextrins (ACDs) with an amino side chain of different lengths at the primary face of β-CD were synthesized and employed in the catalytic synthesis of a series of tetraketones as supramolecular catalysts in water for the first time. Yields of 58-97% were obtained with up to 30 examples of substrate. The catalyst could be recycled easily, while a 92% yield and 84% rate of catalyst recovery could be achieved after 8 cycles of catalyst recycling. Moreover, a catalytic mechanism merging supramolecular catalysis and aminocatalysis could be proposed through detailed 1D and 2D NMR, ESI-MS and Job plot analyses. This protocol retained the promising characteristics of ambient temperature, green medium, simple operation, broad substrate scope, excellent yields, superb catalyst recycling performance and unique catalytic mechanism.

A multicomponent carba-Betti strategy to alkylidene heterodimers-total synthesis and structure-activity relationships of arzanol

Using the synthesis of the heterodimeric phloroglucinyl pyrone arzanol as a benchmark reaction, a carba-version of the Betti multicomponent reaction has been developed. Capitalizing on the fluorous activation of the phenolic component and the use of imini

Synthesis of tetraketones in water and under catalyst-free conditions

A simple, environmentally friendly, tandem Knoevenagel condensation and Michael addition procedure is reported. The reactions between cyclic-13-diketones and a variety of aldehydes were carried out in water to afford tetraketones (64-99%). In this green synthetic protocol, the solvent water itself catalysed the reaction by hydrogen bonding, thus avoiding the use of any other catalysts to make the work up procedure easier.

Ionic liquid promoted and mediated green preparation of arylbispyranylmethane and pyran derivatives and their hybrid with a pyrimidine nucleoside

The utilisation of an ionic liquid-[bmim][BF4] as both reaction medium and promoter for the reaction between aldehyde and 4-hydroxy-6- methylpyran-2-one is described. Without any added catalyst, this reaction was realised efficiently to give arylbispyranylmethane derivatives in high yields. Alternatively, when this reaction was carried out in the presence of acetic anhydride, fused pyran derivatives were obtained. These two novel procedures have advantages such as an environmentally benign nature, high efficiency, simple operation process and mild reaction conditions. As an application, these procedures were used in the preparation of novel 5-substituted pyrimidine nucleoside derivatives with potential antiviral activities.

The Aldol Reaction under High-Intensity Ultrasound: A Novel Approach to an Old Reaction

We have employed high-intensity ultrasound (HIU) to reinvestigate the aldol reaction (AR) in water. A number of aldols that under usual conditions would undergo elimination were isolated in acceptable to good yields. Within 15-30 min, acetophenone reacted with non-enolizable aldehydes to afford the aldol exclusively, while under conventional conditions (stirring or heating under reflux) the same compounds either failed to react or gave, after several hours, the enone, often in complex product mixtures. A library of polyols was obtained starting from a series of acetophenones and excess formaldehyde. Benzaldehyde reacted with a series of 1,3-dicarbonyl compounds to afford the corresponding bis(benzylidene) adducts. The results proved to be highly reproducible because the relevant sonochemical parameters were rigorously controlled. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.