169334-81-0Relevant articles and documents
Highly efficient synthesis of α-aminophosphonates catalyzed by hafnium(IV) chloride
Li, Xiao-Chuan,Gong, Shan-Shan,Zeng, De-Yun,You, Yue-Hai,Sun, Qi
, p. 1782 - 1785 (2016)
A highly efficient one-pot method for the synthesis of a variety of α-aminophosphonates via the one-pot three-component reaction of aldehyde, amine, and phosphite has been developed using only 2 mol % HfCl4 as the catalyst. The NMR evidence strongly indicated the catalytic roles of Hf(IV) on the activation of aldehyde, phosphite, and imine intermediate.
A facile and highly efficient route to α-amino phosphonates via three-component reactions catalyzed by Mg(ClO4)2 or molecular iodine
Wu, Jie,Sun, Wei,Xia, Hong-Guang,Sun, Xiaoyu
, p. 1663 - 1666 (2008/02/11)
Three-component reactions of aldehydes, amines, and diethyl phosphite catalyzed by Mg(ClO4)2 or molecular iodine afforded the corresponding α-amino phosphonates in excellent yields under mild reaction conditions. The Royal Society of Chemistry 2006.
AN EFFICIENT SYNTHESIS OF 1-AMINOPHOSPHONIC ACIDS AND ESTERS BEARING HETEROCYCLIC MOIETY
Boduszek, Bogdan
, p. 63 - 70 (2007/10/03)
New α-aminophosphonic esters and acids derived from furan, thiophene and pyrazole were prepared in high yield, in the reactions of benzylamine, benzhydrylamine or benzyl carbamate with heterocyclic aldehydes and diethyl or diphenyl phosphonates.The protecting groups at amine (benzyl or benzhydryl) were removed by hydrogenolysis or hydrolysis, respectively.The N-benzoyloxycarbonyl (Z-group) was removed by treatment with 45percent HBr in acetic acid. Key words: Diphenyl α-aminofurylmethyl phosphonate, α-aminothienylmethylphosphonic acid, α-aminopyrazolylmethylphosphonic acid, imines, benzyl carbamate.
