169334-96-7Relevant academic research and scientific papers
Synthesis and NMR characterization of diphenyl α-(benzyloxycarbonylamino)benzyl-phosphonates and diphenyl 1-(benzyloxycarbonylamino)-alkyl phosphonates
Consiglio, Giuseppe A.,Failla, Salvatore,Finocchiaro, Paolo,Siracusa, Valentina
, p. 159 - 166 (2007/10/03)
A variety of the title phosphonic derivatives were synthesized in high yields starting from commercially available aldehydes. Complete NMR characterization is reported for all compounds, which are useful intermediates for the synthesis of the phosphorus a
AN EFFICIENT SYNTHESIS OF 1-AMINOPHOSPHONIC ACIDS AND ESTERS BEARING HETEROCYCLIC MOIETY
Boduszek, Bogdan
, p. 63 - 70 (2007/10/03)
New α-aminophosphonic esters and acids derived from furan, thiophene and pyrazole were prepared in high yield, in the reactions of benzylamine, benzhydrylamine or benzyl carbamate with heterocyclic aldehydes and diethyl or diphenyl phosphonates.The protecting groups at amine (benzyl or benzhydryl) were removed by hydrogenolysis or hydrolysis, respectively.The N-benzoyloxycarbonyl (Z-group) was removed by treatment with 45percent HBr in acetic acid. Key words: Diphenyl α-aminofurylmethyl phosphonate, α-aminothienylmethylphosphonic acid, α-aminopyrazolylmethylphosphonic acid, imines, benzyl carbamate.
