16939-37-0

Upstream product

• 99-09-2 3-nitro-aniline 
• 1939-99-7 benzenesulfonyl chloride 

Downstream Products

• 1415114-06-5 N-(3-((5-(4-cyanophenyl)oxazol-2-yl)amino)phenyl)-1-phenylmethanesulfonamide 
• 926203-10-3 N-(3-aminophenyl)-1-phenylmethanesulfonamide 
• 1415114-12-3 N-(3-((5-(isoquinolin-6-yl)oxazol-2-yl)amino)phenyl)-1-phenylmethanesulfonamide 
• 1415114-13-4 N-(3-((5-(1H-indol-2-yl)oxazol-2-yl)amino)phenyl)-1-phenylmethanesulfonamide 
• 1415114-16-7 1-phenyl-N-(3-((5-(4-(trifluoromethyl)phenyl)oxazol-2-yl)amino)phenyl)methanesulfonamide 
• 1415114-81-6 tert-butyl 2-(2-((3-(phenylmethylsulfonamido)phenyl)amino)oxazol-5-yl)-1H-indole-1-carboxylate 
• 187333-33-1 N-methyl-N-(3-nitrophenyl) benzylsulfonamide 

Relevant academic research and scientific papers

Transformation of 3-nitroanilines into dioxoisothiazolo[5,4,3-k,l]acridines

N-Methyl-N-3-nitroaryl benzyl sulfonamides on treatment with t-BuMe2SiCl in the presence of DBU formed silylated oxime derivatives which were photocyclized to the dioxoisothiazolo[5,4,3-k,l]acridine systems. In one example the latter was converted to pyridoacridine derivative.

Aminooxazole Inhibitors of Cyclin Dependent Kinases

Oxazole derivatives are described. The inventive compounds are useful as kinase inhibitors, and may be used in the treatment of cancer, such as prostate cancer, lung cancer, breast cancer, colon cancer, leukemia, CNS cancer, melanoma, ovarian cancer, and