16947-86-7

Basic information

• Product Name: (S)-BOC-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID
• Synonyms: BOC-(S)-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID;(S)-BOC-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID;(S)-3-((tert-Butoxycarbonyl)aMino)-2-(4-MethylphenylsulfonaMido)propanoic acid
• CAS NO: 16947-86-7
• Molecular Formula: C₁₅H₂₂N₂O₆S
• Molecular Weight: 358.41
• Mol File: 16947-86-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Store at 0-5°C
• CAS DataBase Reference: (S)-BOC-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-BOC-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID(16947-86-7)
• EPA Substance Registry System: (S)-BOC-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID(16947-86-7)

Safety Data

• Hazardous Substances Data: 16947-86-7(Hazardous Substances Data)

Usage

General Description

(S)-BOC-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID, also known as Boc-Amino-PTS, is a chemical compound used in the synthesis of peptides and pharmaceuticals. It is a derivative of (S)-2-Amino-3-(p-toluenesulfonamido)propionic acid and is commonly used as a building block for solid-phase peptide synthesis. Boc-Amino-PTS is an important reagent for the protection of amino acids during peptide synthesis. It is a white to off-white crystalline powder that should be stored in a cool, dry place away from light and moisture. (S)-BOC-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID is primarily used in research and development in the pharmaceutical industry.

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 36212-66-5 N²-(toluene-4-sulfonyl)-L-asparagine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 21753-19-5 2-(S)-p-toluenesulfonylamino-β-alanine 
• 1070-19-5 N-(tert-butyloxycarbonyl) azide 

Downstream Products

• 169604-92-6 (S)-3-tert-Butoxycarbonylamino-2-(toluene-4-sulfonylamino)-propionic acid methyl ester 
• 77087-60-6 methyl (S)-2-amino-3-tert-butoxycarbonylaminopropanoate 
• 77087-65-1 (S)-2-({(R)-1-[(S)-2-(2-Benzyloxycarbonylamino-acetylamino)-3-phenyl-propionyl]-pyrrolidine-2-carbonyl}-amino)-3-tert-butoxycarbonylamino-propionic acid 2,4,5-trichloro-phenyl ester 
• 77087-64-0 methyl N-(benzyloxycarbonyl)glycyl-L-phenylalanyl-D-prolyl-N^β-(tert-butoxycarbonyl)-L-α,β-diaminopropanoate 
• 77087-66-2 (S)-2-({(R)-1-[(S)-2-(2-Amino-acetylamino)-3-phenyl-propionyl]-pyrrolidine-2-carbonyl}-amino)-3-tert-butoxycarbonylamino-propionic acid 2,4,5-trichloro-phenyl ester 
• 77100-18-6 cyclo(glycyl-L-phenylalanyl-D-prolyl-N^β-(tert-butoxycarbonyl)-L-α,β-diaminopropanoyl) 
• 58457-98-0 methyl (2S)-2-{[(benzyloxy)carbonyl]amino}-3-[(tert-butoxycarbonyl)amino]propanoate 
• 16947-84-5 N-[(benzyloxy)carbonyl]-3-[(tert-butoxycarbonyl)amino]-L-alanine 
• 199853-65-1 (S)-3-(3-methylbenzyl)amino-2-(4-toluenesulfonyl)amino-1-propanol 
• 199853-71-9 ethyl (S)-N-methyl-N-{3-[N-(3-methylbenzyl)-N-trifluoroacetyl]amino-2-(4-toluenesulfonyl)amino-1-propyl}aminoacetate 
• 199853-67-3 {[[(S)-3-Hydroxy-2-(toluene-4-sulfonylamino)-propyl]-(3-methyl-benzyl)-carbamoyl]-methyl}-methyl-carbamic acid tert-butyl ester 
• 199853-69-5 (S)-3-[N-(3-methylbenzyl)-N-trifluoroacetyl]amino-2-(4-toluenesulfonyl)amino-1-propanol 
• 199853-70-8 (S)-3-[N-(3-methylbenzyl)-N-trifluoroacetylaminomethyl]-1-(4-toluenesulfonyl)aziridine 
• 199853-76-4 N-[(S)-3-Hydroxy-2-(toluene-4-sulfonylamino)-propyl]-2-methylamino-N-(3-methyl-benzyl)-acetamide 

Relevant articles and documents

Asymmetric synthesis of (R)-6-amino-1-methyl-4-(3-methyl- benzyl)hexahydro-1H-1,4-diazepine from L-asparagine

An efficient asymmetric synthesis of (R)-6-amino-1-methyl-4-(3- methylbenzyl)hexahydro-1H-1,4-diazepine [(R)-2] which serves as the amine part of (R)-1, a potent and selective 5-HT3 receptor antagonist, is described. Formation of the hexahydro-

Analogues of the cytostatic cyclic tetrapeptide chlamydocin, Synthesis of N41β-(N-maleoylglycyl) and N41β-(tert-butyloxycarbonyl) derivatives of cyclo (Gly-L-Phe-D-Pro-L-Dap)

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