169498-46-8

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 146398-02-9 tert-butyl (S)-3-benzyloxycarbonylamino-4-hydroxybutyrate 
• 41446-22-4 (S)-3-Benzyloxycarbonylamino-4-isobutoxycarbonyloxy-4-oxo-butyric acid tert-butyl ester 
• 5545-52-8 Z-D(tBu)-OH 

Downstream Products

• 146398-02-9 tert-butyl (S)-3-benzyloxycarbonylamino-4-hydroxybutyrate 
• 668475-45-4 (2R)-2-tert-butoxycarbonylmethyl-aziridine-1-carboxylic acid benzyl ester 
• 944579-68-4 C₄₄H₆₂N₄O₈ 
• 944579-66-2 ethyl (5R)-5-(benzyloxycarbonylamino)-3-oxododecanoate 
• 146398-04-1 (3S)-3-(benzyloxycarbonylamino)-4-(p-toluenesulfonyloxy)-butanoic acid t-butyl ester 
• 350991-20-7 (3R)-3-benzyloxycarbonylamino-decanoic acid 

Relevant academic research and scientific papers

Aziridines derived from amino acids as synthons in pseudopeptide synthesis

The reactivity of the Z-protected aziridine derived from aspartic acid has been studied with various N- and O-nucleophiles. The optimized reaction conditions allow quick and easy access to 1, 2-diamines or amino alcohols. In the case of opening with N-nuc

Towards a biomimetic synthesis of barrenazine A

We report herein a concise and biomimetic synthesis of a precursor of barrenazine A, a cytotoxic alkaloid. The C2-symmetry of this molecule suggested the dimerization of an aminoketone, as the precursor of the central core pyrazine. This compou