169515-92-8

Basic information

• Product Name: (R)-2-Acetylamino-3-[5-(4-fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophen-2-ylsulfanyl]-propionic acid
• Synonyms: (R)-2-Acetylamino-3-[5-(4-fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophen-2-ylsulfanyl]-propionic acid
• CAS NO: 169515-92-8
• Molecular Weight: 493.601
• Mol File: 169515-92-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-2-Acetylamino-3-[5-(4-fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophen-2-ylsulfanyl]-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-Acetylamino-3-[5-(4-fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophen-2-ylsulfanyl]-propionic acid(169515-92-8)
• EPA Substance Registry System: (R)-2-Acetylamino-3-[5-(4-fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophen-2-ylsulfanyl]-propionic acid(169515-92-8)

Safety Data

• Hazardous Substances Data: 169515-92-8(Hazardous Substances Data)

Upstream product

• 2766-43-0 N-tert-butyloxycarbonyl-L-serine methyl ester 
• 108-24-7 acetic anhydride 
• 169515-94-0 C₃₄H₂₄F₂O₄S₆ 
• 169515-95-1 (R)-2-tert-Butoxycarbonylamino-3-[5-(4-fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophen-2-ylsulfanyl]-propionic acid methyl ester 
• 88149-87-5 2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]thiophene 

Downstream Products

• 195704-98-4 (R)-2-Acetylamino-3-[(S)-5-(4-fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophene-2-sulfinyl]-propionic acid 2-methoxy-ethoxymethyl ester 
• 195704-96-2 (R)-2-Acetylamino-3-[5-(4-fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophen-2-ylsulfanyl]-propionic acid 2-methoxy-ethoxymethyl ester 

Relevant articles and documents

Enantioselective total synthesis and structure determination of the mercapturic acid sulfoxide conjugate

A practical and enantioselective total synthesis of the mercapturic acid sulfoxide 4, a metabolite of anti-inflammatory drug DUP 697 1, has been accomplished by employing the substrate-controlled diastereoselective oxidation of the sulfide 7 to the sulfoxide 8 as the key step. This led to the structure determination of 4.