169527-71-3

Basic information

• Product Name: (1S-TRANS)-2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL
• Synonyms: (1S-TRANS)-2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL
• CAS NO: 169527-71-3
• Molecular Formula: C16H24O2
• Molecular Weight: 248.36
• Mol File: 169527-71-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (1S-TRANS)-2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (1S-TRANS)-2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL(169527-71-3)
• EPA Substance Registry System: (1S-TRANS)-2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL(169527-71-3)

Safety Data

• Hazardous Substances Data: 169527-71-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
(1S-TRANS)-2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL is used as an intermediate in the synthesis of pharmaceuticals. Its unique structure and properties make it a valuable component in the development of new drugs and medications.
Used in Agrochemical Synthesis:
In the agrochemical industry, (1S-TRANS)-2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL is utilized as a precursor in the synthesis of various agrochemicals. Its incorporation can lead to the development of more effective and targeted products for agricultural applications.
Used in Material Development:
(1S-TRANS)-2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL may have potential applications in the development of new materials and compounds for industrial use. Its unique properties can contribute to the creation of innovative materials with specific characteristics for various industries.
Used in Research and Development:
Due to its diverse potential applications, (1S-TRANS)-2-(4-TERT-BUTYLPHENOXY)CYCLOHEXANOL is also used in research and development settings. Scientists and researchers explore its properties and potential uses in order to discover new applications and improve existing ones across different fields.

Upstream product

• 286-20-4 cyclohexane-1,2-epoxide 
• 5787-50-8 sodium 4-tert-butylphenolate 
• 507-20-0 tertiary butyl chloride 
• 100256-51-7 2-hydroxycyclohexyl phenyl ether 
• 1942-71-8 (+/-)-2-<4-(tert-butylphenoxy)>cyclohexan-1-ol 
• 130336-25-3 (+/-)-trans-1-acetoxy-2-(4-tert-butylphenoxy)cyclohexane 

Downstream Products

• 1250257-70-5 (1S,2R)-1-tert-butyl-4-(2-chlorocyclohexyloxy)benzene 

Relevant articles and documents

Preparation method of 2-(4-tert-butyl phenoxy) cyclohexanol

The invention, aiming at problems in current preparation of a propargite technical intermediate namely 2-(4-tert-butyl phenoxy) cyclohexanol, provides a preparation method of 2-(4-tert-butyl phenoxy) cyclohexanol. According to the preparation method, cond

Halogenative kinetic resolution of β-aryloxy cyclic alcohols: Chiral BINAP-mediated SN2 displacement of hydroxy groups by chlorides with inversion of stereochemistry

A series of optically active cyclic trans-β-aryloxy alcohols have been obtained by non-enzymatic kinetic resolution of the corresponding racemic aryloxy cyclic alcohols using commercially available (S)-BINAP and NCS by S N2 halogenation of a hydroxy group. The product, cis-β-aryloxy chlorides, was also obtained in optically active form with inversion of the stereochemistry.

A Convenient Enantioselective Synthesis of trans-2-Aryloxycyclohexan-1-ols Using Pig Liver Acetone Powder (PLAP) as Biocatalyst

Pig liver acetone powder (PLAP) has been used as a biocatalyst for enantioselective hydrolysis of racemic trans-1-acetoxy-2-aryloxycyclohexanes to produce the resulting (R,R)-2-aryloxycyclohexan-1-ols upto >99percent enantiomeric purities. (R,R)-Selectivity in this hydrolysis of racemic trans-2-aryloxycyclohexyl acetates was explained on the basis of Jones' three dimensional active site-model.

CONVENIENT ENANTIOSELECTIVE HYDROLYSIS OF RACEMIC trans-1-ACETOXY-2-ARYLOXYCYCLOHEXANES BY CRUDE PIG LIVER ACETONE POWDER (PLAP)

Crude pig liver acetone powder (PLAP) hydrolyzes trans-1-acetoxy-2-aryloxycyclohexanes enantioselectively to produce the corresponding alcohols in high optical purities.