16963-28-3

Upstream product

• 110-91-8 morpholine 
• 589-92-4 1-methylcyclohexan-4-one 
• 98-53-3 4-tercbutyl-cyclohexanone 
• 77412-96-5 1-trifluoromethanesulfonyloxy-4-t-butylcyclohexene 
• 611235-47-3 toluene-4-sulfonic acid 4-tert-butylcyclohex-1-en-1-yl ester 

Downstream Products

• 128920-96-7 cis-4-tert-butyl-2-(3-oxobutyl)cyclohexanone 
• 24817-22-9 8-tert-butylbicyclo<4.4.0>dec-1-en-3-one 
• 68486-90-8 (4R,4aS,6S,8aS)-6-tert-Butyl-3-methyl-8a-morpholin-4-yl-4-phenyl-4a,5,6,7,8,8a-hexahydro-4H-benzo[e][1,2]oxazine 2-oxide 
• 98-53-3 4-tercbutyl-cyclohexanone 
• 132371-01-8 methyl 3-(5-t-butyl-2-oxocyclohexyl)propenoate 
• 83466-10-8 (4R,4aS,7aS)-7a-Morpholin-4-yl-4-phenyl-4,4a,5,6,7,7a-hexahydro-cyclopenta[e][1,2]oxazine 2-oxide 
• 83321-06-6 (4aS,6R,8aS)-6-tert-Butyl-8a-morpholin-4-yl-3-phenyl-4a,5,6,7,8,8a-hexahydro-4H-benzo[e][1,2]oxazine 2-oxide 
• 83321-06-6 (4aS,6S,8aS)-6-tert-Butyl-8a-morpholin-4-yl-3-phenyl-4a,5,6,7,8,8a-hexahydro-4H-benzo[e][1,2]oxazine 2-oxide 
• 80330-97-8 N'-Benzoyl-N-[3-(N'-benzoyl-N-ethoxycarbonyl-hydrazino)-5-tert-butyl-2-oxo-cyclohexyl]-hydrazinecarboxylic acid ethyl ester 
• 16963-14-7 cis-2-acetoxy-4-t-butylcyclohexanone 
• 84736-52-7 (+/-)-(2R,4S)-4-tert-butyl-2-(4'-methoxyphenyl)cyclohexanone 
• 80330-94-5 N'-(5-tert-Butyl-2-oxo-cyclohexyl)-N'-phenyl-hydrazinecarboxylic acid ethyl ester 
• 86296-10-8 (5-tert-Butyl-2-oxo-cyclohexyl)-carbamic acid ethyl ester 
• 98945-58-5 Morpholin-4-yl-carbamic acid ethyl ester 

Relevant academic research and scientific papers

Efficient palladium-catalysed enamide synthesis from enol triflates and enol tosylates

Catalysts generated from Pd2(dba)3 and biphenyl ligands 4 and 7 efficiently promote the coupling of amides and carbamates with unactivated vinyl triflates and tosylates, to provide enamides in good to excellent yields. Georg Thieme V

1 microwave-induced montmorillonite-mediated facile synthesis of enamines

Montmorillonite clay-mediated simple and high yielding protocol for the synthesis of various enamines with secondary amines and ketones is developed under microwave condition. This protocol is very convenient to accesses the enamines from cyclic amines with various carbonyl compounds in high yield under mild reaction conditions with short reaction time.

New bicyclic dioxanes, their preparation and their use as organoleptic compounds

The present invention relates to novel 1,3-dioxane derivatives of formula (I) wherein each of R1 and R2 is a hydrogen atom, R3 and R4 are independently a hydrogen atom, a linear or branched C1-C6 alkyl group, or a linear or branched C2-C6 alkenyl group, and R5 is a linear or branched C1-C6 alkyl group, a linear or branched C2-C6 alkenyl group or a (CH2)0-2 - aryl group, and R6 and R7 are independently a hydrogen atom, a linear or branched C1-C6 alkyl group, a linear or branched C2-C6 alkenyl group or a (CH2)0-2 - aryl group, or R6 and R7 together with the carbon atom to which they are attached form a C5-C6 cycloalkyl group or a C5-C6 cycloalkenyl group, substituted or not; their preparation and their use as organoleptic compounds.

NEW BICYCLIC DIOXANES, THEIR PREPARATION AND THEIR USE AS FRAGRANT COMPOUNDS

The invention is directed to the use of compounds of formula (I), as fragrant agents. In this formula: - R3 and R4 are independently a hydrogen atom, a C1-C6 alkyl group or a C2-C6 alkenyl group, R5 is a C1-C6 alkyl group, a C2-C6 alkenyl group or a (CH2)0-2-aryl group, R6 is a C1 -C6 alkyl group, a C2-C6 alkenyl group, a (CH2)0-2-aryl group or a C5- C6 cycloalkyl or cycloalkenyl group, and R7 is a hydrogen atom, a C1-C6 alkyl group or a C2-C6 alkenyl group; or R3, R4 and R5 are as above defined, and R6 and R7 together with the carbon atom to which they are attached form a C5-C6 cycloalkyl or cycloalkenyl group.

PERFUMING INGREDIENTS WITH ODOR OF THE PHEROMONE TYPE

The present invention relates to β-decalone derivatives (I) svhich can impart useful odor notes of the pheromone/costus type. The present invention doricerns the use of said compounds in the perfumery industry as well as the compositions or articles conta

Palladium catalysed enamine synthesis from vinyl triflates

Vinyl triflates can be converted into the corresponding enamines by treatment with a secondary amine, Cs2CO3 and a catalyst generated from Pd(OAc)2 and rac-BINAP.

Acid-catalyzed Rearrangement of O-4-tert-Butylcyclohexyl Methylthiocarbamates

The geometrical isomers of O-4-tert-butylcyclohexyl methylthiocarbamate were prepared by way of the corresponding dithiocarbamates.The O-trans-isomer was obtained from a mixture of cis- and trans-4-tert-butylcyclohexanols via an alkoxide formation involvi

Structure-odour relationships of some new synthetic sandalwood aroma chemicals. Synthesis and olfactive properties in a series of bicyclodecan-3-ols

The relationship between chemical structure and sandalwood fragrance in a series of four isomers of 8-tert-butylbicyclodecan-3-ol (4a-d), the unsaturated analogue 5 and the methyl-substituted derivative 17 has been examined.The sandalwood fragrance

Stereoselective Reductions of Substituted Cyclohexyl and Cyclopentyl Carbon-Nitrogen ? Systems with Hydride Reagents

Reductions of 3- and 4-substituted cyclohexyl imines, iminium salts, and enamines (via iminium ions) with various hydride reagents reveal that while small reagents (NaBH4, NaBH3CN) favor axial approach as observed with the corresponding ketones, even moderately bulky reagents (i.e., acetoxyboranes) attack preferentially from the equatorial side.This is in direct contrast to the results observed for the same reagents with the corresponding ketones and is interpreted as implying that additional steric interactions induced by the nitrogen substituents encumber axial attack by substituted hydride reagents and force approach from the equatorial direction.The very bulky tri-sec-butylborohydride anion affords highly stereodiscriminating equatorial attack.Reductions of 2-alkylcyclohexyl and 2-alkylcyclopentyl imines and enamines also proceed with high stereoselectivity to give cis-2-alkyl cyclic amines with both hindered and unhindered reagents.This is interpreted to be the result of (1) augmented steric interactions between nitrogen substituents and equatorial 2-alkyl groups (1,3-allylic strain) which induces conformational changes to favor the axial 2-alkyl conformer and (2) hindrance toward equatorial approach by reagents induced by axial alkyl substituents.The result is that equatorial approach is favored with equatorial 2-alkyl conformers and preferential axial approach with axial 2-alkyl conformers, leading to stereoselective production of cis-2-alkylamines. trans-2-n-Propyl-4-tert-butylcyclohexanone is reduced by LiBH(sec-Bu)3 preferentially from the axial direction in contrast to the usual highly selective equatorial attack observed with other cyclohexanones.

The Chemistry of Aryllead(IV) Tricarboxylates. Reaction with Enamines

The treatment of 1-morhpholinocyclopentene (1a) with p-methoxyphenyllead triacetate (2a) in chloroform provides a simple high-yielding route to 2-(4-methoxyphenyl)cyclopentanone (3a).This arylation reaction of enamines has been investigated with a variety of substrates and a number of aryllead triacetates.The reaction has been found to be very sensitive to steric effects and is thus a useful synthetic method in a relatively small number of cases.Acetoxylation is a major competing reaction with those enamines of cyclic ketones which give a low to moderate yield of arylated product.