611235-47-3

Upstream product

• 4124-41-8 p-toluenesulfonylanhydride 
• 98-53-3 4-tercbutyl-cyclohexanone 

Downstream Products

• 93725-77-0 1-(4-tert-butylcyclohex-1-en-1-yl)-4-methylbenzene 
• 16963-28-3 4-t-butyl-1-(morpholin-4-yl)cyclohex-1-ene 
• 1126639-42-6 2-(4-tert-butylcyclohex-1-enyl)benzo[d]oxazole 
• 1262526-22-6 2-(4-t-butylcyclohexene-1-yl)quinoxaline 1-oxide 
• 147678-64-6 1-(4'-tert-butylcyclohex-1-enyl)-3-methoxybenzene 
• 3419-73-6 1-phenyl-4-tert-butylcyclohexene 
• 33061-20-0 1-(4-tert-butylcyclohex-1-en-1-yl)-4-methoxybenzene 
• 1285625-46-8 2-(4-tert-butylcyclohexe-1-enyl)-1,3,5-trimethylbenzene 
• 1397263-74-9 4-tert-butylcyclohexenyl carboxylic acid phenyl ester 
• 23525-05-5 1-bromo-4-(tert-butyl)cyclohex-1-ene 

Relevant academic research and scientific papers

Preparation of α,β-unsaturated esters and amides via external-CO-free palladium-catalyzed carbonylation of alkenyl tosylates

Palladium-catalyzed carbonylation of tosylates with phenyl formate is described. This procedure needs neither external carbon monoxide nor any pressure-resistant apparatus. A variety of cyclic and acyclic alkenyl tosylates can be converted into the corresponding phenyl esters in good yields. Furthermore, this method is effective for the one-pot synthesis of α,β-unsaturated amides.

Kumada coupling of aryl and vinyl tosylates under mild conditions

Aryl and alkenyl tosylates are easily prepared, inexpensive and, thus, attractive for transition-metal-catalyzed couplings, but their reactivity is low. We report examples of mild, palladium-catalyzed coupling of aryl, alkenyl, and alkyl Grignard reagents with aryl and alkenyl tosylates. The resulting biaryls, vinylarenes, and alkylarenes were isolated in good to excellent yield. These couplings were conducted with a nearly equimolar ratio of the two reactants, and many examples were conducted at room temperature.