169674-34-4

Usage

Uses

Used in Scientific Research:
5,6-Difluoro-2-indole carboxylic acid ether ester is used as a research compound for investigating its chemical properties and potential applications in various fields. Its unique molecular structure and reactivity make it a valuable subject for study in the realm of organic chemistry.
Used in Pharmaceutical Applications:
5,6-Difluoro-2-indole carboxylic acid ether ester is used as a potential pharmaceutical agent for the development of new drugs. Its specific molecular structure may offer therapeutic benefits, and further research is needed to explore its potential in treating various medical conditions.
Used in Chemical Synthesis:
5,6-Difluoro-2-indole carboxylic acid ether ester is used as a synthetic intermediate in the production of other complex organic compounds. Its unique functional groups and reactivity make it a useful building block in the synthesis of a wide range of chemical products.
Used in Material Science:
5,6-Difluoro-2-indole carboxylic acid ether ester is used as a component in the development of new materials with specific properties. Its molecular structure may contribute to the creation of materials with unique characteristics, such as improved stability or enhanced reactivity, which could be beneficial in various industries.

InChI:InChI=1/C11H9F2NO2/c1-2-16-11(15)10-4-6-3-7(12)8(13)5-9(6)14-10/h3-5,14H,2H2,1H3

Upstream product

• 609-14-3 2-acetylpropanoic acid ethyl ester 
• 3863-11-4 3,4-difluoroaniline 
• 617-35-6 2-oxo-propionic acid ethyl ester 
• 40594-37-4 (3,4-difluorophenyl)phenylhydrazine hydrochloride 

Downstream Products

• 169674-35-5 5,6-difluoro-1H-indole-2-carboxylic acid 

Relevant academic research and scientific papers

Indole derivative and medical application thereof

The invention discloses an indole compound with FABP4/5 inhibitory activity and a preparation method and medical application of the indole compound. The indole compound is a compound of which the structural formula is shown as a formula I, and pharmaceutically acceptable salt or ester or solvate of the compound. The compound shown in the formula I is a novel FABP4/5 inhibitor and can be used for preparing medicines for preventing or treating FABP4/5 related diseases.

SUBSTITUTED INDOLE COMPOUND

Disclosed is an excellent LXR modulator. A compound represented by the general formula (I): (I) wherein R1, R2, R3 and R4: H, an alkyl which may be substituted, OH, an alkoxy which may be substituted, an amino which may be substituted, a halogeno, a phenyl or the like; R5: H or an alkyl; R6: -COR8 (wherein R8: an alkoxy which may be substituted, a phenyloxy which may be substituted, an amino which may be substituted, or the like), -SO2R9 (wherein R9: an alkyl which may be substituted, a phenyl which may be substituted or a heterocyclyl which may be substituted), or an alkyl which may be substituted; R7: -X2R10 [wherein R10: -COR11 (where R11: OH, an alkoxy which may be substituted or an amino which may be substituted), -SO2R12 (where R12: an alkyl which may be substituted or amino which may be substituted), -N(R13)COR14 (where R13: H or an alkyl which may be substituted; R14: H or an alkyl which may be substituted), -N(R13)SO2R15 (where R13: as defined above; R15: an alkyl which may be substituted) or tetrazol-5-yl; and X2: a single bond or an alkylene which may be substituted]; X1: a methylene which may be substituted; Y1: a phenyl which may be substituted or a heterocyclyl which may be substituted; and Y2: an aryl which may be substituted, a heterocyclyl which may be substituted or the like], or the like.