169686-74-2Relevant academic research and scientific papers
SN2' Ring opening of aziridines bearing an α,β-unsaturated ester group with organocopper reagents. A new stereoselective synthetic route to (E)-alkene dipeptide isosteres
Fujii, Nobutaka,Nakai, Kazuo,Tamamura, Hirokazu,Otaka, Akira,Mimura, Norio,et al.
, p. 1359 - 1372 (2007/10/02)
Regio- and stereo-selective synthesis of (E)-alkene dipeptide isosters has been successfully achieved by exposing both (E)- and (Z)-N-(4-methylphenyl)sulfonyl-γ,δ-epimino-α,β-enoates to organocopper reagents at -78 deg C for 30 min.
