169689-33-2Relevant academic research and scientific papers
α-Alkylation of α-amino esters by using a pyridoxal model compound having a Li+-ionophore character
Miyashita, Kazuyuki,Miyabe, Hideto,Kurozumi, Chiaki,Tai, Kuninori,Imanishi, Takeshi
, p. 12125 - 12136 (2007/10/03)
Synthesis of α,α-dialkyl-α-amino esters by α-alkylation of aldimines prepared from a novel pyridoxal model compound was studied. The α-alkylation of the aldimines having an ethoxy-ethoxy group at C-3 proceeded most rapidly when LiOH was employed as a base and gave α,α-dialkyl-α-amino esters after hydrolysis. The chelated structure composed of the aldimine and Li+ was also revealed by 1H-NMR analysis.
Efficient α-Alkylation of α-Amino Acids by Means of a Novel Pyridoxal Model Compound
Miyashita, Kazuyuki,Miyabe, Hideto,Kurozumi, Chiaki,Imanishi, Takeshi
, p. 487 - 488 (2007/10/03)
α-Alkyl-α-amino esters were prepared by the alkylation of α-imino esters obtained from α-amino acids and a novel PLP model compound possessing a Li+ ionophore character.
