169750-01-0

Basic information

• Product Name: 3-(N-TERT-BUTOXYCARBONYL-N-METHYLAMINO)PYRROLIDINE
• Synonyms: (3S)-3-Amino-N-methylpyrrolidine, N-BOC protected;-tert-Butyl methyl(pyrrolidin-3-yl);3-(N-METHYL-N-BOC-AMINO)PYRROLIDINE;3-(N-METHYL-N-TERT-BUTOXYCARBONYLAMINO)PYRROLIDINE;3-(N-BOC-N-METHYLAMINO)PYRROLIDINE;(3S)-3-[N-(tert-Butoxycarbonyl)-N-methylamino]pyrrolidine;(S)-3-(N-BOCMETHYLAMINO)PYRROLIDINE;(S)-3-[N-(tert-Butoxycarbonyl)-N-methylamino]pyrrolidine
• CAS NO: 169750-01-0
• Molecular Formula: C₁₀H₂₀N₂O₂
• Molecular Weight: 200.28
• Mol File: 169750-01-0.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 268℃
• Flash Point: 116℃
• Appearance: /
• Density: 1.03
• Refractive Index: 1.48
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 9.85±0.10(Predicted)
• CAS DataBase Reference: 3-(N-TERT-BUTOXYCARBONYL-N-METHYLAMINO)PYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(N-TERT-BUTOXYCARBONYL-N-METHYLAMINO)PYRROLIDINE(169750-01-0)
• EPA Substance Registry System: 3-(N-TERT-BUTOXYCARBONYL-N-METHYLAMINO)PYRROLIDINE(169750-01-0)

Safety Data

• Hazardous Substances Data: 169750-01-0(Hazardous Substances Data)

Usage

General Description

3-(N-tert-Butoxycarbonyl-N-methylamino)pyrrolidine is a chemical compound commonly used as a protecting group in peptide synthesis. It is a derivative of pyrrolidine that contains a tert-butoxycarbonyl (Boc) protecting group on the nitrogen atom and a methylamino group. 3-(N-TERT-BUTOXYCARBONYL-N-METHYLAMINO)PYRROLIDINE is utilized to protect the amine group of amino acids during peptide synthesis and can be selectively removed under mild conditions to reveal the reactive amine for further chemical reactions. It is an important tool in the field of organic chemistry for the efficient and selective synthesis of peptides and related compounds.

InChI:InChI=1/C10H20N2O2/c1-10(2,3)14-9(13)7-12-8-4-5-11-6-8/h8,11-12H,4-7H2,1-3H3/t8-/m0/s1

Upstream product

• 1412254-93-3 benzyl (3S)-3-[tert-butoxycarbonyl(methyl)amino]pyrrolidine-1-carboxylate 
• 122536-74-7 (S)-3-<<(1,1-dimethylethoxy)carbonyl>amino>-1-pyrrolidinecarboxylic acid phenylmethyl ester 
• 122536-76-9 3(S)-(tert-butoxycarbonylamino)pyrrolidine 
• 169749-99-9 (3S)-(-)-1-benzyl-3-(methylamino)pyrrolidine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 169750-00-9 (S)-1-benzyl-3-[[N-(t-butoxycarbonyl)]-N-methylamino]pyrrolidine 
• 96568-35-3 1-benzyl-3-(methylamino)pyrrolidine 
• 172477-98-4 1-benzyl-3-<(t-butyloxycarbonyl)methylamino>-pyrrolidine 

Downstream Products

• 762285-62-1 {(S)-1-[((R)-1-Benzyl-pyrrolidin-3-yl)-methyl-carbamoyl]-pyrrolidin-3-yl}-methyl-carbamic acid tert-butyl ester 
• 762285-86-9 {(S)-1-[((S)-1-Benzyl-pyrrolidin-3-yl)-methyl-carbamoyl]-pyrrolidin-3-yl}-methyl-carbamic acid tert-butyl ester 
• 762285-42-7 {(S)-1-[((S)-1-Benzyl-pyrrolidin-3-yl)-methyl-carbamoyl]-pyrrolidin-3-yl}-carbamic acid tert-butyl ester 
• 748183-11-1 tert-Butyl [1-(4-amino-2-chloro-3-fluorophenyl)pyrrolidin-3-yl]methylcarbamate 
• 748183-08-6 tert-Butyl [1-(4-amino-2,5-difluorophenyl)pyrrolidin-3-yl]methylcarbamate 
• 748183-17-7 tert-Butyl [1-(4-amino-2-trifluoromethylphenyl)pyrrolidin-3-yl]methylcarbamate 
• 748183-03-1 tert-Butyl [1-(4-amino-2,3-difluorophenyl)pyrrolidin-3-yl]methylcarbamate 
• 748183-04-2 tert-Butyl [1-(4-amino-2-bromophenyl)pyrrolidin-3-yl]methylcarbamate 
• 748183-20-2 tert-Butyl [1-(4-amino-2-hydroxymethylphenyl)pyrrolidin-3-yl]methylcarbamate 
• 748183-18-8 tert-Butyl [1-(5-amino-4-methylpyridin-2-yl)pyrrolidin-3-yl]methylcarbamate 
• 748183-05-3 tert-Butyl [1-(4-amino-2,6-difluorophenyl)pyrrolidin-3-yl]methylcarbamate 
• 748183-13-3 tert-Butyl [1-(4-amino-5-chloro-2-methylphenyl)pyrrolidin-3-yl]methylcarbamate 
• 748183-00-8 tert-Butyl [1-(4-amino-3-bromophenyl)pyrrolidin-3-yl]methylcarbamate 
• 748183-21-3 tert-Butyl [1-(4-amino-3-chloro-2-cyanophenyl)pyrrolidin-3-yl]methylcarbamate 

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