169750-01-0

Basic information

• Product Name: 3-(N-TERT-BUTOXYCARBONYL-N-METHYLAMINO)PYRROLIDINE
• Synonyms: (3S)-3-Amino-N-methylpyrrolidine, N-BOC protected;-tert-Butyl methyl(pyrrolidin-3-yl);3-(N-METHYL-N-BOC-AMINO)PYRROLIDINE;3-(N-METHYL-N-TERT-BUTOXYCARBONYLAMINO)PYRROLIDINE;3-(N-BOC-N-METHYLAMINO)PYRROLIDINE;(3S)-3-[N-(tert-Butoxycarbonyl)-N-methylamino]pyrrolidine;(S)-3-(N-BOCMETHYLAMINO)PYRROLIDINE;(S)-3-[N-(tert-Butoxycarbonyl)-N-methylamino]pyrrolidine
• CAS NO: 169750-01-0
• Molecular Formula: C₁₀H₂₀N₂O₂
• Molecular Weight: 200.28
• Mol File: 169750-01-0.mol

Chemical Properties

• Boiling Point: 268℃
• Flash Point: 116℃
• Appearance: /
• Density: 1.03
• Refractive Index: 1.48
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 9.85±0.10(Predicted)
• CAS DataBase Reference: 3-(N-TERT-BUTOXYCARBONYL-N-METHYLAMINO)PYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(N-TERT-BUTOXYCARBONYL-N-METHYLAMINO)PYRROLIDINE(169750-01-0)
• EPA Substance Registry System: 3-(N-TERT-BUTOXYCARBONYL-N-METHYLAMINO)PYRROLIDINE(169750-01-0)

Safety Data

• Hazardous Substances Data: 169750-01-0(Hazardous Substances Data)

Usage

Uses

Used in Organic Chemistry:
3-(N-TERT-BUTOXYCARBONYL-N-METHYLAMINO)PYRROLIDINE is used as a protecting group for the amine group of amino acids during peptide synthesis for its ability to shield the reactive amine group, allowing for selective and efficient chemical reactions to occur without unwanted side reactions.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-(N-TERT-BUTOXYCARBONYL-N-METHYLAMINO)PYRROLIDINE is used as a key intermediate in the synthesis of peptide-based drugs, facilitating the production of complex peptide structures with high purity and yield. Its selective removal under mild conditions ensures the integrity of the final peptide product, contributing to the development of effective therapeutic agents.
Used in Research and Development:
3-(N-TERT-BUTOXYCARBONYL-N-METHYLAMINO)PYRROLIDINE is utilized in research and development for the exploration of novel peptide sequences and their potential applications in medicine and biotechnology. Its role in protecting the amine group of amino acids during synthesis allows for the investigation of various peptide modifications and their effects on biological activity and stability.

InChI:InChI=1/C10H20N2O2/c1-10(2,3)14-9(13)7-12-8-4-5-11-6-8/h8,11-12H,4-7H2,1-3H3/t8-/m0/s1

Upstream product

• 172477-98-4 1-benzyl-3-<(t-butyloxycarbonyl)methylamino>-pyrrolidine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 96568-35-3 1-benzyl-3-(methylamino)pyrrolidine 
• 169750-00-9 (S)-1-benzyl-3-[[N-(t-butoxycarbonyl)]-N-methylamino]pyrrolidine 
• 169749-99-9 (3S)-(-)-1-benzyl-3-(methylamino)pyrrolidine 
• 122536-76-9 3(S)-(tert-butoxycarbonylamino)pyrrolidine 
• 122536-74-7 (S)-3-<<(1,1-dimethylethoxy)carbonyl>amino>-1-pyrrolidinecarboxylic acid phenylmethyl ester 
• 1412254-93-3 benzyl (3S)-3-[tert-butoxycarbonyl(methyl)amino]pyrrolidine-1-carboxylate 

Downstream Products

• 863401-94-9 tert-butyl methyl(1-(5-nitropyridin-2-yl)pyrrolidin-3-yl)carbamate 
• 946056-08-2 (1-{5-[(biphenyl-4-carbonyl)-amino]-pyridin-2-yl}-pyrrolidin-3-yl)-methyl-carbamic acid tert-butyl ester 
• 863401-75-6 methyl-[1-(4-nitro-phenyl)-pyrrolidin-3-yl]-carbamic acid tert-butyl ester 
• 643087-83-6 tert-butyl [1-(4-aminophenyl)pyrrolidin-3-yl]methylcarbamate 
• 863401-89-2 biphenyl-4-carboxylic acid [4-(3-methylamino-pyrrolidin-1-yl)-phenyl]-amide 
• 863401-88-1 (1-{4-[(biphenyl-4-carbonyl)-amino]-phenyl}-pyrrolidin-3-yl)-methyl-carbamic acid tert-butyl ester 
• 172478-04-5 3-methylamino-1-propionyl-pyrrolidine 
• 838871-78-6 tert-butyl {1-[2-amino-6-(3-cyanophenyl)pyrimidin-4-yl]-pyrrolidin-3-yl}methylcarbamate 
• 762285-60-9 C₁₉H₃₀N₂O₂ 
• 859731-43-4 2-(3-(R/S)-(((tert-butoxycarbonyl)amino)methyl)-pyrrolidin-1-yl)-4-(4-methoxybenzyl)-7-oxo-4,7-dihydro[1,3]thiazolo[4,5-b]pyridine-6-carboxylic acid 
• 895571-39-8 (1-{2-[7-(3-fluoro-benzenesulfonyl)-chroman-4-yl]-ethyl}-pyrrolidin-3-yl)-methyl-carbamic acid tert-butyl ester 
• 748183-11-1 tert-Butyl [1-(4-amino-2-chloro-3-fluorophenyl)pyrrolidin-3-yl]methylcarbamate 

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