96568-35-3Relevant academic research and scientific papers
Antibacterial compounds
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Page/Page column 17, (2010/02/12)
Bacterial protein synthesis-inhibiting compounds having formula (I) and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates in the processes, compositions containing the compounds, and methods of using the compounds are disclosed.
Monocyclic Analogues of the μ-Opioid Agonist 3,8-Diazabicyclooctanes: Synthesis, Modeling, and Activity
Barlocco, Daniela,Villa, Stefania,Fratta, Walter,Fadda, Paola,Colombo, Diego,Toma, Lucio
, p. 11547 - 11556 (2007/10/02)
Several monocyclic derivatives structurally related to the μ-opioid agonist 3-cinnamyl-8-propionyl-3,8-diazabicyclooctane have been synthesized and tested in binding studies using the μ-selective 3H-DAMGO as ligand.Modeling studies have been performed on the same compounds in order to explain the observed lack of affinity towards μ-opioid receptors.
Antibacterial 7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives
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, (2008/06/13)
The present invention relates to a 1,8-naphthyridine derivative of the formula STR1 wherein R1, R2 and R3 are the same or different and each hydrogen or lower alkyl having 1 to 5 carbon atoms; and esters thereof and salts thereof and processes for preparation thereof. These compounds show excellent antibacterial activity and are useful antibacterial agents.
