169750-99-6 Usage
Description
(3S)-(+)-1-Benzyl-3-(ethylamino)pyrrolidine, a chiral compound with the molecular formula C15H22N2, features a pyrrolidine ring adorned with a benzyl group and an ethylamino group. (3S)-(+)-1-BENZYL-3-(ETHYLAMINO)PYRROLIDINE is notable for its specific optical rotation properties, indicative of its (3S)-(+)-enantiomer configuration. Its unique three-dimensional structure and chemical properties make it a valuable building block in organic synthesis and chemical research, with potential applications in pharmaceutical development and various industrial processes.
Uses
Used in Organic Synthesis:
(3S)-(+)-1-Benzyl-3-(ethylamino)pyrrolidine is used as a building block in organic synthesis for the creation of more complex compounds. Its unique structure allows for the development of a wide range of chemical entities with diverse applications.
Used in Chemical Research:
In the field of chemical research, (3S)-(+)-1-Benzyl-3-(ethylamino)pyrrolidine serves as a valuable compound for studying the properties and reactions of chiral molecules, contributing to a deeper understanding of stereochemistry and its implications in various chemical processes.
Used in Pharmaceutical Development:
(3S)-(+)-1-Benzyl-3-(ethylamino)pyrrolidine is used as a precursor in the development of pharmaceutical drugs. Its unique chemical structure may offer novel therapeutic opportunities, particularly in the design of enantioselective drugs that can interact with biological targets in a highly specific manner.
Used in Industrial Processes:
(3S)-(+)-1-BENZYL-3-(ETHYLAMINO)PYRROLIDINE may also find applications in various industrial processes, where its specific chemical properties can be harnessed for the production of specialty chemicals, materials, or other products that require the precision of chiral compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 169750-99-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,7,5 and 0 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 169750-99:
(8*1)+(7*6)+(6*9)+(5*7)+(4*5)+(3*0)+(2*9)+(1*9)=186
186 % 10 = 6
So 169750-99-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H20N2/c1-2-14-13-8-9-15(11-13)10-12-6-4-3-5-7-12/h3-7,13-14H,2,8-11H2,1H3/t13-/m0/s1
169750-99-6Relevant articles and documents
Development of selective inhibitors for the treatment of rheumatoid arthritis: (R)-3-(3-(Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)-3-oxopropanenitrile as a JAK1-selective inhibitor
Chough, Chieyeon,Joung, Misuk,Lee, Sunmin,Lee, Jaemin,Kim, Jong Hoon,Kim, B. Moon
, p. 1495 - 1510 (2018/02/19)
A series of 3(R)-aminopyrrolidine derivatives were designed and synthesized for JAK1-selective inhibitors through the modification of tofacitinib's core structure, (3R,4R)-3-amino-4-methylpiperidine. From the new core structures, we selected (R)-N-methyl-N-(pyrrolidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine as a scaffold for further SAR studies. From biochemical enzyme assays and liver microsomal stability tests, (R)-3-(3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)pyrrolidin-1-yl)-3-oxopropanenitrile (6) was chosen for further in vivo test through oral administration. Compound 6 showed improved selectivity for JAK1 compared to that of tofacitinib (IC50 11, 2.4 × 102, 2.8 × 103, and 1.1 × 102 nM for JAK1, JAK2, JAK3, and TYK2, respectively). In CIA and AIA model tests, compound 6 exhibited similar efficacy to tofacitinib citrate.
BIS-PYRIDYLPYRIDONES AS MELANIN-CONCENTRATING HORMONE RECEPTOR 1 ANTAGONISTS
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Page/Page column 23-24, (2009/07/17)
The invention provides novel bis-pyridylpyridones which are antagonists at the melanin-concentrating hormone receptor 1 (MCHR1), pharmaceutical compositions containing them, processes for their preparation, and their use in therapy and for the treatment of obesity and/or diabetes.
