169758-66-1 Usage
Uses
NAD 299 Hydrochloride is a selective, high affinity 5-HT1A antagonist, used in psychotropic drug development.
Biological Activity
Selective, high affinity 5-HT 1A receptor antagonist (K i = 0.6 nM in vitro ).
Check Digit Verification of cas no
The CAS Registry Mumber 169758-66-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,7,5 and 8 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 169758-66:
(8*1)+(7*6)+(6*9)+(5*7)+(4*5)+(3*8)+(2*6)+(1*6)=201
201 % 10 = 1
So 169758-66-1 is a valid CAS Registry Number.
InChI:InChI=1/C18H23FN2O2/c19-16-8-7-14(18(20)22)15-9-13(10-23-17(15)16)21(11-3-1-4-11)12-5-2-6-12/h7-8,11-13H,1-6,9-10H2,(H2,20,22)/t13-/m1/s1
169758-66-1Relevant articles and documents
Process for the manufacture of 3-N-N-dicyclobutylamino-8-fluoro-3, 4-dihydro-2H-1-benzopyran-5-carboxamide
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, (2008/06/13)
A process for the manufacture of the racemic compound of the formula (I), its R-enantiomer (formula R-(I)) and its S-enantiomer (formula S-(I)), and pharmaceutically acceptable salts and/or solvates thereof, as well as new intermediates obtained and used in the process.
Combination of 5-HT uptake inhibitor with a selective 5-HT1A antagonist
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, (2008/06/13)
The invention relates to a combination of a first component (a) which is a 5-HT reuptake inhibitor and a second component (b) which is selective 5-HT 1A antagonist of the general formula wherein R 1 is n-propyl or cyclobutyl; R 2 is isopropyl, tertiary bu
