169766-19-2

Upstream product

• 169766-18-1 Diphenyl-carbamic acid 9-((2R,3aS,9aR)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-2-[3-(2,2,2-trifluoro-acetylamino)-propylamino]-9H-purin-6-yl ester 
• 169766-17-0 2,2,2-Trifluoro-N-{3-[6-oxo-9-((2R,3aS,9aR)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-6,9-dihydro-1H-purin-2-ylamino]-propyl}-acetamide 
• 169766-16-9 2-(3-Amino-propylamino)-9-((2R,3aS,9aR)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-2-yl)-1,9-dihydro-purin-6-one 
• 136834-39-4 2-chloro-2'-deoxyinosine 
• 154920-36-2 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-2-chloro-2'-deoxyinosine 

Downstream Products

• 169766-20-5 Diphenyl-carbamic acid 9-{(2R,4S,5R)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-2-[3-(2,2,2-trifluoro-acetylamino)-propylamino]-9H-purin-6-yl ester 

Relevant academic research and scientific papers

Oligonucleotides bearing cationic groups: N2-(3-aminopropyl)deoxyguanosine. Synthesis, enhanced binding properties and conjugation chemistry

A phosphoramidite with an aminopropyl group placed at the N2-position of 2'-deoxyguanosine has been synthesized and incorporated into oligonucleotides. This modification shows enhanced binding properties against both DNA and RNA targets and is useful for conjugating other functionalities.