169809-64-7Relevant academic research and scientific papers
Ruthenium-Catalyzed Heck-Type Alkenylation of Alkyl Bromides
Mu?oz-Molina, José María,Pérez, Pedro J.
, p. 8289 - 8296 (2019/06/24)
The complex [CpRuCl(PPh3)2] displays a high catalytic activity for the Heck-type alkenylation of alkyl bromides in the first example using this metal under thermal conditions. The coupling reaction proceeds efficiently with a variety of functionalized tertiary, secondary, and primary alkyl bromides. The presence of Hünig's base has been revealed to be crucial for this transformation. Preliminary mechanistic studies support the participation of alkyl radicals in the reaction.
Regioselective Copper-Catalyzed Oxidative Coupling of α-Alkylated Styrenes with Tertiary Alkyl Radicals
Wang, Cong,Liu, Rui-Hua,Tian, Ming-Qing,Hu, Xu-Hong,Loh, Teck-Peng
, p. 4032 - 4035 (2018/07/15)
A radical-mediated oxidative cross-coupling of readily accessible α-alkylated styrenes with 1,3-dicarbonyl compounds utilizing a combination of Cu(OAc)2 and air as a catalytic system is described. Rather than requiring α-halocarbonyl compounds, this efficient approach enables direct installation of tertiary functionalized alkyl motifs to olefins with simple carbonyl derivatives. The novel protocol is characterized with high allylic selectivities via a competing β-H elimination. Both radical-clock and -trapping experiments provided clear-cut evidence for the intermediacy of an α-keto carbon-centered radical.
General and facile method for exo -methlyene synthesis via regioselective C-C double-bond formation using a copper-amine catalyst system
Nishikata, Takashi,Nakamura, Kimiaki,Itonaga, Kohei,Ishikawa, Shingo
supporting information, p. 5816 - 5819 (2015/02/19)
In this study, for distal-selective β-hydride elimination to produce exomethylene compounds with a newly formed Csp3-Csp3 bond between tertiary alkyl halides and -alkylated styrenes, a combination of a Cu(I) salt and a pyridine-based amine ligand (TPMA) is found to be a very efficient catalyst system. The yields and regioselectivities were high, and the regioselectivity was found to be dependent on the structure of the alkyl halide, with bulky alkyl halides showing the highest distal selectivities.
ALLYLIC CHAIN TRANSFER AGENTS
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, (2008/06/13)
PCT No. PCT/AU94/00672 Sec. 371 Date Aug. 1, 1996 Sec. 102(e) Date Aug. 1, 1996 PCT Filed Nov. 2, 1994 PCT Pub. No. WO95/12568 PCT Pub. Date May 11, 1995A process for the free radical initiated polymerization of unsaturated species characterized by the us
