169809-64-7Relevant articles and documents
Ruthenium-Catalyzed Heck-Type Alkenylation of Alkyl Bromides
Mu?oz-Molina, José María,Pérez, Pedro J.
, p. 8289 - 8296 (2019/06/24)
The complex [CpRuCl(PPh3)2] displays a high catalytic activity for the Heck-type alkenylation of alkyl bromides in the first example using this metal under thermal conditions. The coupling reaction proceeds efficiently with a variety of functionalized tertiary, secondary, and primary alkyl bromides. The presence of Hünig's base has been revealed to be crucial for this transformation. Preliminary mechanistic studies support the participation of alkyl radicals in the reaction.
General and facile method for exo -methlyene synthesis via regioselective C-C double-bond formation using a copper-amine catalyst system
Nishikata, Takashi,Nakamura, Kimiaki,Itonaga, Kohei,Ishikawa, Shingo
supporting information, p. 5816 - 5819 (2015/02/19)
In this study, for distal-selective β-hydride elimination to produce exomethylene compounds with a newly formed Csp3-Csp3 bond between tertiary alkyl halides and -alkylated styrenes, a combination of a Cu(I) salt and a pyridine-based amine ligand (TPMA) is found to be a very efficient catalyst system. The yields and regioselectivities were high, and the regioselectivity was found to be dependent on the structure of the alkyl halide, with bulky alkyl halides showing the highest distal selectivities.
