169836-72-0Relevant academic research and scientific papers
Synthesis of phosphorodithioate DNA by the H-phosphonothioate method
Seeberger, Peter H.,Caruthers, Marvin H.,Bankaitis-Davis, Danute,Beaton, Graham
, p. 5759 - 5772 (2007/10/03)
A novel method for the efficient synthesis phosphorodithioate DNA using H-phosphonothioate synthons is described. The 5'-DMT-nucleotide H- phosphonothioate monomers were prepared in two high yielding steps, from commercially, available phosphoramidites. T
Oxidative formation of phosphorodithioates via H-phosphonodithioates
Seeberger, Peter H.,Caruthers, Marvin H.
, p. 695 - 698 (2007/10/02)
H-Phosphonodithioate esters can be linked to a second alcohol via an oxidative coupling procedure to generate a phosphorodithioate diester. Nucleoside-cholesterol and nucleoside-amino acid phosphorodithioates were synthesized via this route.
