169888-82-8

Basic information

• Product Name: diethyl <4-(methoxy)methoxy>phenylmalonate
• CAS NO: 169888-82-8
• Molecular Weight: 296.32
• Mol File: 169888-82-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl <4-(methoxy)methoxy>phenylmalonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl <4-(methoxy)methoxy>phenylmalonate(169888-82-8)
• EPA Substance Registry System: diethyl <4-(methoxy)methoxy>phenylmalonate(169888-82-8)

Safety Data

• Hazardous Substances Data: 169888-82-8(Hazardous Substances Data)

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 155627-09-1 ethyl <4-(methoxy)methoxy>phenylacetate 
• 17138-28-2 (4-hydroxy-phenyl)-acetic acid ethyl ester 
• 156-38-7 4-hydroxyphenylacetate 

Downstream Products

• 169888-76-0 2-<4-(methoxy)methoxy>phenyl-1,3-propanediol 

Relevant articles and documents

On the optimization of pig pancreatic lipase catalyzed monoacetylation of prochiral diols

The effect of various experimental variables (solvent, methodology of supportation on celite, presence of water, conversion and so on) on the rate and on the enantioselectivity of monoacetylation of some prochiral 2-substituted-1,3-propanediols with vinyl acetate catalyzed by crude PPL (pig pancreatic lipase) was analyzed. This study allowed to assess the best conditions for performing these transformations, providing an efficient methodology for the synthesis of valuable chiral building blocks with moderate amounts of inexpensive PPL, which can also be easily recycled.