155627-09-1Relevant articles and documents
Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process for Making Them, and Use Thereof for Treating Pain and Other Conditions
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Page/Page column 42, (2009/07/03)
Vanilloid receptor ligand compounds corresponding to formula I: pharmaceutical compositions containing such compounds, a process for producing such compounds, and methods of using such compounds for treating or inhibiting pain and various other disorders or conditions.
Synthetic studies on aphidicolane and stemodane diterpenes. II. Neighboring hydroxyl group participation in stereoselective syntheses of tricyclo[6.3.1.01,6]dodecanes corresponding to the B/C/D-ring systems
Iwata,Murakami,Okuda,Morie,Maezaki,Yamashita,Kuroda,Imanishi,Tanaka
, p. 1900 - 1905 (2007/10/02)
Tricyclo[6.3.1.01,6]dodecane derivatives (5 and 6) corresponding to the B/C/D-ring systems of aphidicolane and stemodane diterpenes were synthesized stereoselectively via a spirodienone-alcohol (4) as a common intermediate. Participation of the neighboring hydroxyl group in 4 is crucial for controlling the stereochemistry of the spirocenters.