169894-34-2Relevant academic research and scientific papers
Diastereoselective addition-elimination reactions of lithium enolates of chiral N-acyloxazolidinones with 2-methylene-3-phenoxyalkanoates
Kanno,Osanai
, p. 1503 - 1506 (2007/10/02)
Addition-elimination reaction of lithium enolates 2 of N-acyloxazolidinones with 2-methylene-3-phenoxyalkanoates 3 and 10 proceeded diastereoselectively and regiospecifically to give chiral N-[(E)-4-alkoxycarbonyl-4-pentenoyl]oxazolidinones 4 and 12a, whi
Diastereoselective palladium(0)-catalyzed reactions of lithium enolates of chiral N-acyloxazolidinones. Asymmetric synthesis of 2-substituted (E)-4- alkylidenepentanedioates
Kanno,Osanai
, p. 5375 - 5378 (2007/10/02)
The palladium(0)-catalyzed reactions of lithium enolates 1 of N- acyloxazolidinones with 3-acetoxy-2-methylenealkanoates 2, easily prepared via DABCO-catalyzed coupling of corresponding aldehydes with acrylates, proceeded diastereoselectively and regioselectively to give chiral N-((E)-4- alkoxycarbonyl-4-pentenoyl)oxazolidinones 3, useful intermediates of metallopeptidase inhibitors.
