169894-53-5Relevant academic research and scientific papers
Diastereoselective palladium(0)-catalyzed reactions of lithium enolates of chiral N-acyloxazolidinones. Asymmetric synthesis of 2-substituted (E)-4- alkylidenepentanedioates
Kanno,Osanai
, p. 5375 - 5378 (1995)
The palladium(0)-catalyzed reactions of lithium enolates 1 of N- acyloxazolidinones with 3-acetoxy-2-methylenealkanoates 2, easily prepared via DABCO-catalyzed coupling of corresponding aldehydes with acrylates, proceeded diastereoselectively and regioselectively to give chiral N-((E)-4- alkoxycarbonyl-4-pentenoyl)oxazolidinones 3, useful intermediates of metallopeptidase inhibitors.
