169899-65-4Relevant academic research and scientific papers
Synthetic studies on bryostatins, potent antineoplastic agents: Synthesis of the C17-C;27 fragment of C20 deoxybryostatins
Ohmori, Ken,Suzuki, Takayuki,Nishiyama, Shigeru,Yamamura, Shosuke
, p. 6515 - 6518 (1995)
Synthetic process toward the bottom-half portion of C20 deoxygenated series of bryostatins is described. It is noted that the neighboring group participation consisting of a six-membered ring enabled introduction of an unsaturated bond required for the characteristic α,β-unsaturated ester of the bryostatins.
