16990-40-2Relevant academic research and scientific papers
Synthesis of indoles from o,β-dinitrostyrenes via indium/acetic acid-mediated Reductive heterocyclizations
Lee, Geunsoo,Choi, Jaehwan,Lee, Byung Min,Kim, Byeong Hyo
, p. 155 - 162 (2013/03/13)
Reductive heterocyclization reactions of various 1-nitro-2-(2-nitroaryl) ethenes to indoles were investigated. In the presence of indium/AcOH in toluene or benzene, 1-nitro-2-(2-nitroaryl)ethenes were cyclized to give corresponding indoles in good yields.
Studies of new indole alkaloid coupling methods for the synthesis of haplophytine
Rege, Pankaj D.,Tian, Yuan,Corey
, p. 3117 - 3120 (2007/10/03)
The two novel bisindole alkaloid structures shown can be synthesized in a few steps from the canthiphytine derivative 9.
A general large scale synthesis of 2-alkyl-7-methoxyindoles
Chen, Bang-Chi,Hynes Jr., John,Pandit, Chennagiri R.,Zhao, Rulin,Skoumbourdis, Amanda P.,Wu, Hong,Sundeen, Joseph E.,Leftheris, Katerina
, p. 951 - 960 (2007/10/03)
A general method has been developed for the large scale synthesis of 2-alkyl-7-methoxyindoles and analogs. This method involves an efficient preparation of the key intermediates, 1-(2-nitroaryl)-2-nitroalkanols and 1-(2-nitroaryl)-2-nitroalkenes, and affords 2-alkyl-7-methoxyindoles and analogs in 3 steps with good overall yields.
