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Androsta-1,4-diene-3,17-diol, (3β,17β)-, also known as 4-Androstene-3,17-dione, is a naturally occurring steroid compound. It is a key intermediate in the synthesis of various anabolic steroids and pharmaceuticals due to its unique structure. Androsta-1,4-diene-3,17-diol,(3b,17b)- (9CI) is characterized by the presence of a double bond between carbons 1 and 4, and hydroxyl groups at the 3 and 17 positions. Its chemical formula is C19H30O2, and it has a molecular weight of 294.44 g/mol. The compound is classified under the CAS number 521-18-6 and is often abbreviated as 4-AD or A1D. It is important to note that the use of Androsta-1,4-diene-3,17-diol,(3b,17b)- (9CI) in the production of anabolic steroids is subject to regulatory controls due to their potential health risks and misuse in sports.

16992-51-1

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16992-51-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 16992-51-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,9,9 and 2 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 16992-51:
(7*1)+(6*6)+(5*9)+(4*9)+(3*2)+(2*5)+(1*1)=141
141 % 10 = 1
So 16992-51-1 is a valid CAS Registry Number.

16992-51-1Downstream Products

16992-51-1Relevant academic research and scientific papers

New synthesis of estradiol from androsta-1,4-diene-3,17-dione

Vasiljeva,Demin,Kochev,Lapitskaya,Pivnitsky

, p. 593 - 595 (1999)

A new method for the aromatization of ring A in androsta-1,4-diene-3,17-dione, available from sterols by means of the microbiological degradation of the side chain, was developed. The method consists of the reduction of androsta-1,4-diene-3,17-dione to the corresponding dienediol followed by double C,O-deprotonation of ring A, accompanied by expulsion of the 19-methyl group and formation of estradiol in a high yield.

Reduction of steroidal ketones with amine - Boranes

Leontjev,Vasiljeva,Pivnitsky

, p. 703 - 708 (2007/10/03)

Complexes of secondary amines with borane, R2NH·BH 3, surpass sodium borohydride as reducing agents for saturated and unsaturated steroidal 3-, 12-, 17-, and 20-ketones as regards chemo- and regioselectivity and mildness of the reaction conditions. In the case of 12-ketones, stereoselectivity is also improved.

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