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846-48-0 Usage

Description

Boldenone is the chemical precursor of its endecylenate ester prodrug boldenone undecylenate – which is used extensively as a steroid for animals, mainly horses and cattle, under the brand name Equipoise, among others. For this application, it is injected to improve the weight, hair coat, appetite, and general physical condition of horses affected by disease, anorexia, or overwork. It is also used as an illegal doping agent for human athletes. As a derivative of testosterone, it retains its anabolic strength, but exhibits reduced androgenic effects.

Chemical Properties

Crystalline Solid

Sources

https://en.wikipedia.org/wiki/Boldenone_undecylenate
https://en.wikipedia.org/wiki/Boldenone
https://www.drugs.com/vet/equipoise.html
https://www.steroidal.com/steroid-profiles/equipoise/
https://www.evolutionary.org/equipoise-boldenone-undecylenate

Definition

ChEBI: An 3-oxo-Delta1,Delta4-steroid substituted by an oxo group at position 3 and a beta-hydroxy group at position 17. It is an anabolic androgenic steroid that has been eveloped for veterinary use.

Brand name

Equipoise [Veterinary] (Fort Dodge Animal Health).

Uses

Boldenone is an anabolic steroid. Controlled substance.

Uses

Controlled substance. Anabolic steroid
InChI:InChI=1/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,11,14-17,21H,3-6,8,10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1

846-48-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name boldenone

1.2 Other means of identification

Product number -
Other names 1,2-didehydrotestosterone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:846-48-0 SDS

846-48-0Synthetic route

testosterone
58-22-0

testosterone

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

Conditions
ConditionsYield
With tert-butyldimethylsilyl chloride; 2,3-dicyano-5,6-dichloro-p-benzoquinone In 1,4-dioxane at 0 - 20℃; for 40h;74%
With selenium(IV) oxide
With selenious acid
With old yellow enzyme from Geobacillus kaustophilus at 70℃; for 48h; pH=7; aq. phosphate buffer; Enzymatic reaction; regioselective reaction;
mit Hilfe von Corynebacterium simplex;
Androsta-1,4-diene-3,17-dione
897-06-3

Androsta-1,4-diene-3,17-dione

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

Conditions
ConditionsYield
for 336h; Rhodotorula mucilaginosa;64%
With potato dextrose broth medium In ethanol at 24 - 26℃; for 96h; Penicillium decumbens ATCC 10436;3%
cholesterol
57-88-5

cholesterol

A

testosterone
58-22-0

testosterone

B

Androstenedione
63-05-8

Androstenedione

C

Androsta-1,4-diene-3,17-dione
897-06-3

Androsta-1,4-diene-3,17-dione

D

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

E

2-[(8S,9S,10R,13S,14S)-10,13-Dimethyl-3-oxo-3,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-cyclopenta[a]phenanthren-(17Z)-ylidene]-propionic acid methyl ester
79694-52-3

2-[(8S,9S,10R,13S,14S)-10,13-Dimethyl-3-oxo-3,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-cyclopenta[a]phenanthren-(17Z)-ylidene]-propionic acid methyl ester

F

22-hydroxy-23,24-bisnor-1,4-choladien-3-one
71658-22-5

22-hydroxy-23,24-bisnor-1,4-choladien-3-one

Conditions
ConditionsYield
With Mycobacterium sp. CCM 3529 Product distribution;A 0.01 g
B 0.03 g
C 51%
D 0.06 g
E n/a
F 0.38 g
Androsta-1,4-diene-3,17-dione
897-06-3

Androsta-1,4-diene-3,17-dione

A

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

B

11α,17β-dihydroxyandrosta-1,4-dien-3-one
30915-20-9

11α,17β-dihydroxyandrosta-1,4-dien-3-one

Conditions
ConditionsYield
With phosphate buffer; Beauveria sp. culture at 28℃; for 24h;A 38%
B 46%
With phosphate buffer; Beauveria sp. culture at 28℃; for 24h; Yield given. Yields of byproduct given;
Epiandrosterone
481-29-8

Epiandrosterone

A

testosterone
58-22-0

testosterone

B

3β,11α-dihydroxy-5α-androstan-17-one
25848-75-3

3β,11α-dihydroxy-5α-androstan-17-one

C

3beta-7alpha-Dihydroxy-5alpha-androstane-17-one
25848-68-4

3beta-7alpha-Dihydroxy-5alpha-androstane-17-one

D

3beta-7beta-Dihydroxy-5alpha-androstane-17-one
25848-69-5

3beta-7beta-Dihydroxy-5alpha-androstane-17-one

E

1α,3β-dihydroxy-5α-androstan-17-one
2260-01-7

1α,3β-dihydroxy-5α-androstan-17-one

F

Androsta-1,4-diene-3,17-dione
897-06-3

Androsta-1,4-diene-3,17-dione

G

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

I

5α-androst-1-ene-3,17-dione
571-40-4

5α-androst-1-ene-3,17-dione

J

6β-hydroxy-4-androstene-3,17-dione
63-00-3

6β-hydroxy-4-androstene-3,17-dione

Conditions
ConditionsYield
With malt extract; disodium hydrogenphosphate; calcium(II) chloride dihydrate; magnesium(II) chloride hexahydrate; strontium (III) chloride hexahydrate; potassium chloride; boric acid; sodium hydrogencarbonate; sodium sulfate; sodium chloride; potassium bromide; potassium hydroxide In water; N,N-dimethyl-formamide at 32℃; for 168h; pH=8; Enzymatic reaction;A 2%
B 2%
C 2%
D 3%
E 5%
F 5%
G 3%
H 2%
I 2%
J 32%
2,4,6-trimethyl-pyridine
108-75-8

2,4,6-trimethyl-pyridine

2α,4α-dibromo-17β-hydroxy-5α-androstan-3-one
119369-73-2

2α,4α-dibromo-17β-hydroxy-5α-androstan-3-one

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

Androsta-1,4-diene-3,17-dione
897-06-3

Androsta-1,4-diene-3,17-dione

A

testosterone
58-22-0

testosterone

B

Androstenedione
63-05-8

Androstenedione

C

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

Conditions
ConditionsYield
at 25℃; for 72h; stereoselective reduction in the biotransformation by cell suspension cultures of Marchantia Polymorpha, other androsterone derivative;
With Mycobacterium sp. No. 22 for 24h; Microbiological reaction;A n/a
B n/a
C 0.5 g
With unidentified fungal species isolated from grinded corn In water at 37℃; for 1h; pH=7; aq. phosphate buffer; Microbiological reaction; Enzymatic reaction;
Progesterone
57-83-0

Progesterone

A

testosterone
58-22-0

testosterone

B

pregna-1,4-diene-3,20-dione
1162-54-5

pregna-1,4-diene-3,20-dione

C

Androstenedione
63-05-8

Androstenedione

D

testosterone acetate
1045-69-8

testosterone acetate

E

11-alpha-hydroxyprogesterone
80-75-1

11-alpha-hydroxyprogesterone

F

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

Conditions
ConditionsYield
With immobilized spores of Aspergillus ochraceus; Tris-maleate buffer at 30℃; for 48h; Product distribution; Mechanism; various water activity of the biocatalysts;
17β-acetoxy-androstadien-(1.4)-one-(3)

17β-acetoxy-androstadien-(1.4)-one-(3)

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

Conditions
ConditionsYield
With potassium hydroxide
2α.4α-dibromo-17β-hydroxy-androstanone-(3)

2α.4α-dibromo-17β-hydroxy-androstanone-(3)

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

Conditions
ConditionsYield
With 2,3,5-trimethyl-pyridine
With Potassium benzoate; toluene; butan-1-ol Erhitzen des Reaktionsprodukts unter 6 Torr auf 220-230grad;
Androstenedione
63-05-8

Androstenedione

A

testosterone
58-22-0

testosterone

B

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction
2: unidentified fungal species isolated from grinded corn / water / 1 h / 37 °C / pH 7 / aq. phosphate buffer; Microbiological reaction; Enzymatic reaction
View Scheme
1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

Conditions
ConditionsYield
With zinc In tetrahydrofuran Heating;96%
1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

testolactone
968-93-4

testolactone

Conditions
ConditionsYield
With Penicillium notatum KCH 904 In water; acetone at 27℃; for 96h; Enzymatic reaction;90%
1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

17β-O-tert-butyldimethylsilylandrosta-1,4-dien-3-one
102054-23-9

17β-O-tert-butyldimethylsilylandrosta-1,4-dien-3-one

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide Ambient temperature;89%
With 1H-imidazole In N,N-dimethyl-formamide for 4.5h; Ambient temperature;83%
1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

acetic acid
64-19-7

acetic acid

17a-acetoxy-androst-1,4-dien-3-one

17a-acetoxy-androst-1,4-dien-3-one

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In toluene at 40℃; for 0.5h;83%
formic acid
64-18-6

formic acid

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In toluene at 40℃; for 0.5h;82%
1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

1-bromo-2,3,4-tri-O-acetyl-α-D-glucuronic acid methyl ester
21085-72-3

1-bromo-2,3,4-tri-O-acetyl-α-D-glucuronic acid methyl ester

methyl (androsta-1,4-dien-17β-ol-3-one)-17-O-2,3,4-tri-O-acetyl-β-D-glucuronate
1177368-54-5

methyl (androsta-1,4-dien-17β-ol-3-one)-17-O-2,3,4-tri-O-acetyl-β-D-glucuronate

Conditions
ConditionsYield
With cadmium(II) carbonate In toluene for 6h; Koenigs-Knorr synthesis; Heating;80%
1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

benzoic acid
65-85-0

benzoic acid

3-oxoandrosta-1,4-dien-17α-yl benzoate
150054-81-2

3-oxoandrosta-1,4-dien-17α-yl benzoate

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In toluene at 40℃; for 0.5h;80%
1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

bis-(2-methyl-1H-imidazol-1-yl)methanone
13551-83-2

bis-(2-methyl-1H-imidazol-1-yl)methanone

3-oxoandrosta-1,4-dien-17β-yl-2'-methyl-1H-imidazole-1-carboxylate
1138159-98-4

3-oxoandrosta-1,4-dien-17β-yl-2'-methyl-1H-imidazole-1-carboxylate

Conditions
ConditionsYield
In dichloromethane for 28h; Heating;73%
1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

2-(1,1-Dimethyl-prop-2-ynylperoxy)-2-methyl-pentane
98406-40-7

2-(1,1-Dimethyl-prop-2-ynylperoxy)-2-methyl-pentane

Methacryloyl chloride
920-46-7

Methacryloyl chloride

3,17β-dimethacryloyloxy-3-(3-methyl-3-tert-pentylperoxybut-1-ynyl)-androsta-1,4-diene

3,17β-dimethacryloyloxy-3-(3-methyl-3-tert-pentylperoxybut-1-ynyl)-androsta-1,4-diene

Conditions
ConditionsYield
Stage #1: 2-(1,1-Dimethyl-prop-2-ynylperoxy)-2-methyl-pentane With n-butyllithium In hexane at -40 - -20℃; for 1h;
Stage #2: 1-dehydrotestosterone In diethyl ether; hexane at 15 - 20℃; for 18h;
Stage #3: Methacryloyl chloride In diethyl ether; hexane at 0 - 20℃; for 19h;
66%
1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

Androsta-1,4-diene-3,17-dione
897-06-3

Androsta-1,4-diene-3,17-dione

Conditions
ConditionsYield
for 336h; Rhodotorula mucilaginosa;54%
1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

A

14α,17β-dihydroxyandrosta-1,4-dien-3-one
58105-34-3

14α,17β-dihydroxyandrosta-1,4-dien-3-one

B

6β,17β-dihydroxyandrosta-1,4-dien-3-one

6β,17β-dihydroxyandrosta-1,4-dien-3-one

Conditions
ConditionsYield
With fungus Cephalosporium aphidicola In ethanol for 120h; hydroxylation;A 2%
B 48%
1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

thioacetic acid
507-09-5

thioacetic acid

A

1α-acetylthio-17β-hydroxy-4-androsten-3-one
99371-90-1

1α-acetylthio-17β-hydroxy-4-androsten-3-one

B

1α-acetylthio-17β-hydroxy-4-androsten-3-one 17-acetat
116104-58-6

1α-acetylthio-17β-hydroxy-4-androsten-3-one 17-acetat

Conditions
ConditionsYield
In chloroform at 40℃; for 24h;A 47%
B 16%
1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

A

[1-2H]4-methylestra-1,3,5(10)-trien-17β-ol

[1-2H]4-methylestra-1,3,5(10)-trien-17β-ol

B

[1α-2H]testosterone

[1α-2H]testosterone

C

[1α,3ξ-2H2]androst-4-ene-3ξ,17β-diol
898529-69-6

[1α,3ξ-2H2]androst-4-ene-3ξ,17β-diol

Conditions
ConditionsYield
With lithium aluminium deuteride In tetrahydrofuran for 0.25h; Heating;A 31%
B 18%
C 28%
1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

A

[1α-2H]testosterone

[1α-2H]testosterone

B

[1α,3ξ-2H2]androst-4-ene-3ξ,17β-diol
898529-69-6

[1α,3ξ-2H2]androst-4-ene-3ξ,17β-diol

Conditions
ConditionsYield
With sodium borodeuteride In tetrahydrofuran for 0.25h; Heating;A 15%
B 30%
1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

thiophenol
108-98-5

thiophenol

1α-phenylthio-17β-hydroxyandrost-4-ene-3-one

1α-phenylthio-17β-hydroxyandrost-4-ene-3-one

Conditions
ConditionsYield
With sodium ethanolate In ethanol for 3h; Heating;20%
1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

11α,17β-dihydroxyandrosta-1,4-dien-3-one
30915-20-9

11α,17β-dihydroxyandrosta-1,4-dien-3-one

Conditions
ConditionsYield
for 72h; Rhizopus arrhizus ATCC 11145;13%
quinoline
91-22-5

quinoline

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

estradiol
50-28-2

estradiol

Conditions
ConditionsYield
at 370 - 390℃;
at 370 - 390℃;
butanoic acid anhydride
106-31-0

butanoic acid anhydride

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

17β-butyryloxy-androsta-1,4-dien-3-one

17β-butyryloxy-androsta-1,4-dien-3-one

Conditions
ConditionsYield
With pyridine
tetralin
119-64-2

tetralin

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

estradiol
50-28-2

estradiol

Conditions
ConditionsYield
at 370 - 390℃;
at 370 - 390℃;
thioacetic acid
507-09-5

thioacetic acid

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

1α-acetylthio-17β-hydroxy-4-androsten-3-one
99371-90-1

1α-acetylthio-17β-hydroxy-4-androsten-3-one

pentanoic anhydride
2082-59-9

pentanoic anhydride

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

17β-valeryloxy-androsta-1,4-dien-3-one

17β-valeryloxy-androsta-1,4-dien-3-one

Conditions
ConditionsYield
at 130℃;
1,2-Dihydronaphthalene
447-53-0

1,2-Dihydronaphthalene

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

estradiol
50-28-2

estradiol

Conditions
ConditionsYield
at 370 - 390℃;
at 370 - 390℃;
9,10-dihydrophenanthrene
776-35-2

9,10-dihydrophenanthrene

1-dehydrotestosterone
846-48-0

1-dehydrotestosterone

A

estradiol
50-28-2

estradiol

B

4-methyl-estratriene-(1.3.5(10))-diol-(1.17β)
3597-39-5

4-methyl-estratriene-(1.3.5(10))-diol-(1.17β)

Conditions
ConditionsYield
at 390℃;

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