16994-13-1Relevant academic research and scientific papers
Compound used as RET kinase inhibitor and application thereof
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Paragraph 0294-0296; 0301-0302, (2021/07/01)
The invention relates to a compound used as an RET kinase inhibitor and application thereof, wherein the compound has a structure as shown in a formula F, has good inhibition capability on RET kinase, and has good pharmacodynamic and pharmacokinetic performance and lower toxic and side effects.
Photolabile compound and substrate for oligomer probe array with the same
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Page/Page column 12, (2009/08/14)
Provided is a substrate for an oligomer probe array to which a photolabile material having an acetylene derivative is directly attached or attached via a linker.
Photolabile compound, oligomer probe array and substrate for oligomer probe array containing the same, and manufacturing method of the same
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Page/Page column 29, (2008/12/07)
A photolabile compound, an oligomer probe array, and a susbtrate for oligomer probe array comprising the same, and a manufacturing method of the same are disclosed. wherein, X is or R1 is hydrogen, an alkyl group, or an acetyl group, R2 is hydrogen, methyl, ethyl, propyl, or phenyl.
Site-specific labelling of caged ATP with deuterium or 18oxygen
Corrie,Reid
, p. 289 - 300 (2007/10/02)
[3-D]2-Nitroacetophenone and [alcohol-18O]-1-(2-nitrophenyl)ethyl alcohol were prepared and used to synthesise labelled P3-1-(2-nitrophenyl)ethyl esters of ATP ('caged ATP') with isotope present either as deuterium on the 3-position of the nitrosubstituted ring or as 18oxygen in the bridging position between the terminal phosphate and the nitrophenylethyl group. The availability of the deuterated compounds enabled complete assignment of their 1H NMR spectra.
